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Recruiting NCT06912230

Hypoxia, Appetite, and Energy Intake in Young Female Adults

Trial Parameters

Condition Hypoxia
Sponsor University of Ottawa
Study Type INTERVENTIONAL
Phase N/A
Enrollment 10
Sex FEMALE
Min Age 18 Years
Max Age 30 Years
Start Date 2024-11-13
Completion 2025-12
Interventions
NormoxiaHypoxia (simulated altitude of 5000 meters above sea-level)

Brief Summary

The goal of this clinical trial is to investigate the effects of acute passive continuous hypoxemia (simulated high-altitude at rest) on appetite and energy intake in healthy young female adults. The main questions it aims to answer are: * Does six hours of simulated high-altitude (5000 meters) reduce scores of subjective appetite and energy intake? * Do changes in appetite and energy intake persist in the hours following the end of hypoxic exposure? Researchers will compare the effects of simulated high-altitude to a control normoxia (sea-level) condition to see if exposure to low oxygen levels independently affect appetite and energy intake. Participants will: * Visit the laboratory for a preliminary screening session to assess eligibility. * Undergo two randomized, single-blind, experimental sessions consisting of six hours of passive exposure to normoxia or hypoxia in a climate-controlled chamber. * Consume foods provided from a curated list, served in ad libitum quantities, after leaving the laboratory to assess post-exposure energy intake.

Eligibility Criteria

Inclusion Criteria: * English or French speaking * Ability to provide informed consent Exclusion Criteria: * History or evidence of chronic disease * Current use of hypolipemic medication * Current use of hormonal contraceptives * Current use of antidepressants * Current use of anticoagulants * Ongoing smoking status * Experiencing pregnancy, puerperium, or irregular menstrual cycles

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