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Recruiting NCT04093986

Hydroxyurea Exposure Limiting Pregnancy and Follow-Up Lactation

Trial Parameters

Condition Sickle Cell Disease
Sponsor Children's Hospital Medical Center, Cincinnati
Study Type OBSERVATIONAL
Phase N/A
Enrollment 200
Sex ALL
Min Age N/A
Max Age N/A
Start Date 2019-12-22
Completion 2025-12
Interventions
Chart ReviewSurvey

Brief Summary

The purpose of this research study is to document and understand the effects of hydroxyurea exposure for women with SCD and their babies, during both gestation and lactation.

Eligibility Criteria

Inclusion Criteria: * Medical records or data available from previous clinical care prior to June 20, 2019 of pregnant females with SCD, including women who miscarried, had a still birth, or completed labor at any gestational stage, with any hydroxyurea exposure during either pregnancy and/or while breastfeeding. * Medical records or data available from previous clinical care prior to June 20, 2019 about pregnancy and breastfeeding outcomes, both for babies with hydroxyurea exposure and other babies by these same women. Exclusion Criteria: * Unavailable medical records or lack of information about hydroxyurea exposure.

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