NCT06642324 Human Papillomavirus Association and Genomic Exploration in Head-Neck Squamous Cell Carcinomas
| NCT ID | NCT06642324 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh |
| Condition | Head Neck Cancer |
| Study Type | OBSERVATIONAL |
| Enrollment | 550 participants |
| Start Date | 2024-04-30 |
| Primary Completion | 2025-03-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 550 participants in total. It began in 2024-04-30 with a primary completion date of 2025-03-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Head and neck squamous cell carcinoma (HNSCC) represents a significant public health burden in Bangladesh with a high incidence and mortality rate. While traditional risk factors like tobacco and betel nut chewing contribute to HNSCC incidence, the emergence of HPV-associated HNSCC presents a unique challenge. The main goal of this observational study is to explore the prevalence, risk factors, and biological mechanisms underlying food habits and HPV-driven HNSCC in the population and identify the genomic changes and characteristics related to this malignancy. This study will provide the prevalence of HPV-associated HNSCC and screening the HPV typing in the Bangladeshi population, identify risk factors, and any biologically driven mechanisms causing HNSCC.
Eligibility Criteria
Inclusion Criteria: 1. Patient Age: adult (\> 18 years) 2. Head and neck squamous cell carcinoma diagnosed by biopsy (Histopathology confirmed HNSCC). 3. Diagnosed cases specific Head-Neck sub-sites: (oral cavity, oropharynx, hypopharynx, larynx, tongue) 4. Patient's Consent Exclusion Criteria: 1. Patient Age: children (\< 18 years) 2. Cancers of any part of the body other than the head-neck region. 3. People without HNSCC 4. Any chronic diseases, genetic diseases, acute/chronic infectious diseases, etc. -
Contact & Investigator
S M Rashed Ul Islam, M. Phil, MPH
PRINCIPAL INVESTIGATOR
Bangabandhu Sheikh Mujib Medical University (BSMMU)
Frequently Asked Questions
Who can join the NCT06642324 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Head Neck Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06642324 currently recruiting?
Yes, NCT06642324 is actively recruiting participants. Contact the research team at smrashed@bsmmu.edu.bd for enrollment information.
Where is the NCT06642324 trial being conducted?
This trial is being conducted at Dhaka, Bangladesh.
Who is sponsoring the NCT06642324 clinical trial?
NCT06642324 is sponsored by Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh. The principal investigator is S M Rashed Ul Islam, M. Phil, MPH at Bangabandhu Sheikh Mujib Medical University (BSMMU). The trial plans to enroll 550 participants.
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