How Early Mobilization Impacts on Diaphragm Thickness in Critically Ill Children
This study examines whether children on breathing machines who receive early physical movement and exercises have better muscle strength in their diaphragm (the breathing muscle) compared to children receiving standard care. Researchers will measure the thickness of the diaphragm to see if early movement helps prevent muscle weakness that can occur during critical illness.
Key Objective: The trial tests whether early mobilization can prevent diaphragm muscle weakness and improve breathing muscle function in critically ill children on ventilators.
Who to Consider: Parents of critically ill children requiring mechanical ventilation who are interested in exploring whether early physical activity might help preserve their child's breathing muscle strength.
Trial Parameters
Brief Summary
The objective is to compare the impact of early mobilization and routine care on diaphragm thickness in critically ill children
Eligibility Criteria
Inclusion Criteria: * subjects \> 6 months and \< 12 years of age； * subjects been intubated and mechanically ventilated for \< 24 hours at the time of screening; * the Glasgow Coma Scale (GCS) on admission of Pediatric Intensive Care Unit (PICU) is greater than 3 Exclusion Criteria: * cardiopulmonary arrest; * history of diaphragmatic paralysis or neuromuscular disease; * neuromuscular blockade; * expectation to be liberated from ventilator in \< 24 hours * history of mechanical ventilation in the last 6 months * presence of tracheostomy * high cervical spine injury * status convulsion * thoracic trauma when ultrasonic examination cannot be performed