HMB and Exercise-induced Muscle Damage
Trial Parameters
Brief Summary
The study aims at assessing the influence of β-hydroxy-β-methylbutyrate (HMB) supplementation (4.0 g/day) supplemented for 7 days in a group of speed-strength trained individuals on lower-body strength performance, selected muscle histological, molecular and blood markers of muscle recovery in response to resistance exercise-induced muscle damage.
Eligibility Criteria
Inclusion Criteria: * written informed consent from all participants before the study * a current medical clearance to practice sports, * training experience: at least 1 year strength training programs that include lower limbs, * minimum of 3 workout sessions (strength/resistance training) a week, * protein intake in customary diet and during the study protocol \> 1.6g / kg of body mass per day, * individual maximum strength greater than 2.5 times the body weight for the 1RM test in the leg-press. Exclusion Criteria: * current injury, * any health-related contraindication, * declared general feeling of being unwell, * unwilling to follow the study protocol, * serious disease or metabolic problems, * intake of creatine, caffeine or beta-alanine, or other ergogenic supplements 3 months before the beginning of the study, * history of anabolic androgenic steroids or drugs use that may interfere with muscle mass control (eg, corticosteroids), or affect physical performance, * smoking and to