NCT07841158 Histological and Histomorphometric Assessment With Inflammatory Profile Analysis of Bone Tissue After Horizontal Ridge Augmentation Using Customized Porous Zirconia Shell
| NCT ID | NCT07841158 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Mohammed Mahmoud Abed |
| Condition | Alveolar Bone Loss |
| Study Type | INTERVENTIONAL |
| Enrollment | 10 participants |
| Start Date | 2025-03-15 |
| Primary Completion | 2027-05-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 10 participants in total. It began in 2025-03-15 with a primary completion date of 2027-05-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this clinical study is to learn whether a custom-made porous zirconia shell can support good-quality new bone when widening the lower back jaw before dental implant placement. The study includes adults whose jawbone in this area is too narrow for implants (Seibert Class I defects). The main question it aims to answer is: What is the quality of the new bone formed under a porous zirconia shell, and how much inflammation does the tissue show? Participants will: * Receive gum treatment and a CBCT scan before surgery * Have bone augmentation surgery, in which a digitally designed porous zirconia shell is fixed over a mixture of their own bone and xenograft * Return after 2 weeks for suture removal and a check of the wound * Return after 6 months for a CBCT scan, removal of the shell, collection of a small bone sample (biopsy), and dental implant placement
Eligibility Criteria
Inclusion Criteria: * Age more than 21 years old * Horizontal bone loss in the lower posterior area (Seibert Class I) * Enough inter-arch space for placement of implant-supported prosthesis * Motivated patient to have the treatment * Good oral hygiene Exclusion Criteria: * Patients with systemic conditions that could interfere with the healing process * Pregnant females * Smokers * Poor oral hygiene
Contact & Investigator
Nada Abdelmonem Zazou, PhD
STUDY DIRECTOR
October University for Modern Sciences and Arts (MSA)
Frequently Asked Questions
Who can join the NCT07841158 clinical trial?
This trial is open to participants of all sexes, aged 21 Years or older, studying Alveolar Bone Loss. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07841158 currently recruiting?
Yes, NCT07841158 is actively recruiting participants. Contact the research team at mohammed.mahmoud12@msa.edu.eg for enrollment information.
Where is the NCT07841158 trial being conducted?
This trial is being conducted at Giza, Egypt.
Who is sponsoring the NCT07841158 clinical trial?
NCT07841158 is sponsored by Mohammed Mahmoud Abed. The principal investigator is Nada Abdelmonem Zazou, PhD at October University for Modern Sciences and Arts (MSA). The trial plans to enroll 10 participants.