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Recruiting NCT04449666

Hippocampal Volume and Memory Functions in Aneurysmal Subarachnoid Hemorrhage

Trial Parameters

Condition Neurologic Disorder
Sponsor BDH-Klinik Hessisch Oldendorf
Study Type OBSERVATIONAL
Phase N/A
Enrollment 30
Sex ALL
Min Age 18 Years
Max Age 70 Years
Start Date 2020-06-15
Completion 2026-06-15
Interventions
Neuropsychological assessment and structural MRI

Brief Summary

Neuropsychological and functional long-term consequences of subarachnoid hemorrhages (SAH) represent a great challenge, since sometimes considerable cognitive deficits occur without evidence of substantial brain damage. In this study, we want to examine if the frequently observed memory deficits are associated with hippocampal atrophy.

Eligibility Criteria

Inclusion Criteria: * neurological rehabilitation patients in phase B - D * at minimum eight weeks after disease onset * aneurysmal subarachnoid hemorrhage (Hunt \& Hess grade I or II) * written consent from the patient's legal representative * exclusion of pregnancy Exclusion Criteria: * insufficient cardiorespiratory stability * previous brain damage * mental disorders (dementia, depression) * colonization with multi-resistant pathogens * MRI contraindications * claustrophobia * weight \> 120 kg

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