NCT06416488 High-Intensity Interval Training(HIIT) on Cardio-metabolic Risk in School-age Children
| NCT ID | NCT06416488 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Children's Hospital of Fudan University |
| Condition | Cardiovascular Syndrome, Metabolic |
| Study Type | INTERVENTIONAL |
| Enrollment | 336 participants |
| Start Date | 2024-07-13 |
| Primary Completion | 2027-09 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 336 participants in total. It began in 2024-07-13 with a primary completion date of 2027-09.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study aims to evaluate the health promotion effects of high-intensity interval training (HIIT) intervention on school-age children who are at high risk for cardiovascular disease (CVD), as well as the long-term adherence and acceptability of HIIT in this population for future application.
Eligibility Criteria
Inclusion Criteria: * Aged 7-18 years at baseline. * At least one of the following cardio-metabolic abnormalities: 1. Prediabetes (Impaired fasting glucose: 5.6 ≤ fasting blood glucose level ≤ 6.9 mmol/L; or Impaired glucose tolerance: 7.8 ≤ blood glucose level after 2 hours postprandial ≤ 11.0 mmol/L). 2. Lipid abnormalities (High-density lipoprotein cholesterol ≤ 1.04 mmol/L; or Low-density lipoprotein cholesterol ≥ 3.37 mmol/L; or Triglycerides ≥ 1.70 mmol/L, or Total cholesterol ≥ 5.18 mmol/L). 3. Elevated blood pressure (Systolic/diastolic blood pressure consistently higher than the 90th percentile for gender, age, and height; or systolic/diastolic blood pressure ≥ 120/80 mmHg). * Written consent from participants and their guardians. Exclusion Criteria: * Previously diagnosed with heart failure, severe malnutrition, immune deficiency, liver or kidney disease, cancer, or other diseases deemed unsuitable for participation. * Taking weight loss drugs, or undergone weight loss surgery. * Attending behavior-based intervention programs (exercise or diet) within a year. * Regular HIIT (at least once per week). * Secondary obesity, such as neuropsychiatric disorders, endocrine disorders, sleep apnea syndrome, or other conditions. * Unable to take interventions due to health conditions, such as joint diseases, fractures, injuries. * Other situations unsuitable for participation.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06416488 clinical trial?
This trial is open to participants of all sexes, aged 7 Years or older, up to 18 Years, studying Cardiovascular Syndrome, Metabolic. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06416488 currently recruiting?
Yes, NCT06416488 is actively recruiting participants. Contact the research team at wennanhe@fudan.edu.cn for enrollment information.
Where is the NCT06416488 trial being conducted?
This trial is being conducted at Shanghai, China.
Who is sponsoring the NCT06416488 clinical trial?
NCT06416488 is sponsored by Children's Hospital of Fudan University. The trial plans to enroll 336 participants.