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Recruiting NCT06968312

NCT06968312 Hexadecanal as an Addon to Cognitive Processing Therapy for PTSD

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Clinical Trial Summary
NCT ID NCT06968312
Status Recruiting
Phase
Sponsor Tel Aviv University
Condition Post Traumatic Stress Disorder (PTSD)
Study Type INTERVENTIONAL
Enrollment 40 participants
Start Date 2025-05-05
Primary Completion 2026-09-30

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Cognitive Processing Therapy + HexadecanalHexadecanal - Molecule Distribution in the Therapy room

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 40 participants in total. It began in 2025-05-05 with a primary completion date of 2026-09-30.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This RCT investigates whether Cognitive Processing Therapy, a first line treatment for PTSD, can be enhanced by the use of the odor molecule Hexadecenal (HEX). HEX is secreted from body odor and has been shown to promotes psychological well-being and positive social interaction. For the active group Hex will be diffused in the treatment room during all treatment sessions. For the control group a vehicle placebo molecule will be diffused. Both therapists and patients will be blind to study condition.

Eligibility Criteria

Inclusion Criteria: * Diagnosis of PTSD according to DSM-5 * Age 18 years and over * Eligible for CPT treatment at the National Center for Traumatic Stress and Resilience Exclusion Criteria: * Bipolar disorder, psychosis, neurological disorders * Drug Addiction * Parallel psychotherapy * Congenital or acquired anosmia.

Contact & Investigator

Central Contact

Yair Bar Haim, PhD

✉ yair1@tauex.tau.ac.il

📞 03-6405465

Principal Investigator

Yair Bar Haim, PhD

PRINCIPAL INVESTIGATOR

Tel Aviv University

Frequently Asked Questions

Who can join the NCT06968312 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Post Traumatic Stress Disorder (PTSD). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06968312 currently recruiting?

Yes, NCT06968312 is actively recruiting participants. Contact the research team at yair1@tauex.tau.ac.il for enrollment information.

Where is the NCT06968312 trial being conducted?

This trial is being conducted at Tel Aviv, Israel.

Who is sponsoring the NCT06968312 clinical trial?

NCT06968312 is sponsored by Tel Aviv University. The principal investigator is Yair Bar Haim, PhD at Tel Aviv University. The trial plans to enroll 40 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology