| NCT ID | NCT04008147 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Swiss Federal Institute of Technology |
| Condition | Iron Deficiency Anemia of Pregnancy |
| Study Type | INTERVENTIONAL |
| Enrollment | 30 participants |
| Start Date | 2019-07-03 |
| Primary Completion | 2025-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 30 participants in total. It began in 2019-07-03 with a primary completion date of 2025-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Gestational diabetes mellitus (GDM), defined as hyperglycemia with blood glucose values above normal but below those diagnostic of DM, and iron deficiency (ID) with or without anemia (IDA) are common during pregnancy. Both disease patterns are associated with an increased risk of complications during pregnancy and at delivery and may have a variety of negative effects on different aspects of child development. Thus, GDM and ID/IDA during pregnancy should be prevented. Whether iron supplementation with high oral doses acutely increases hepcidin during pregnancy, and whether this acute iron-induced increase in hepcidin decreases insulin sensitivity, is uncertain.
Eligibility Criteria
Inclusion Criteria: * week of pregnancy 24-28 * pre-pregnancy BMI \<27.5kg/m2 * singleton pregnancy * Hb \> 8.0 g/dl Willing to either: * not take any iron supplements for 14 days (however, participants will receive a similar amount of total iron during the 4 study days that they would normally receive over 14 days) OR * to take the multivitamin "Burgerstein Schwangerschaft and Stillzeit" supplements over the 14 days (contains 30 mg iron) Exclusion Criteria: * iron infusion within the past 6 months * severely anemic Hb\<8.0g/dl * acute or chronic disease * long-term medication * medical problems known to affect iron homeostasis * smoking
Contact & Investigator
Frequently Asked Questions
Who can join the NCT04008147 clinical trial?
This trial is open to female participants only, aged 18 Years or older, up to 45 Years, studying Iron Deficiency Anemia of Pregnancy. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04008147 currently recruiting?
Yes, NCT04008147 is actively recruiting participants. Contact the research team at nicole.stoffel@hest.ethz.ch for enrollment information.
Where is the NCT04008147 trial being conducted?
This trial is being conducted at Zurich, Switzerland.
Who is sponsoring the NCT04008147 clinical trial?
NCT04008147 is sponsored by Swiss Federal Institute of Technology. The trial plans to enroll 30 participants.