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Recruiting NCT05575024

NCT05575024 Hemodynamic Stability in Septic Shock Patients Undergoing Continuous Renal Replacement Therapy With oXiris Membrane

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Clinical Trial Summary
NCT ID NCT05575024
Status Recruiting
Phase
Sponsor Seoul National University Hospital
Condition Acute Kidney Injury Due to Sepsis
Study Type OBSERVATIONAL
Enrollment 98 participants
Start Date 2024-01-01
Primary Completion 2026-06-30

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL
Interventions
oXiris membranePolysulfone membrane

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 98 participants in total. It began in 2024-01-01 with a primary completion date of 2026-06-30.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The new adsorbing membrane for continuous renal replacement therapy (CRRT), oXiris, can reduce plasma cytokines and endotoxins in septic shock patients with severe acute kidney injury, compared with standard membranes. However, its hemodynamic stability or benefits have not been thoroughly evaluated although this is reasonable.

Eligibility Criteria

Inclusion Criteria: * Aged ≥ 18 years * Sepsis related acute kidney injury requiring continuous renal replacement therapy Exclusion Criteria: • No monitoring of blood pressure and ECG

Contact & Investigator

Central Contact

Seung Seok Han, M.D.

✉ hansway7@snu.ac.kr

📞 82-2-2072-4785

Principal Investigator

Seung Seok Han, M.D.

PRINCIPAL INVESTIGATOR

Seoul National University Hospital

Frequently Asked Questions

Who can join the NCT05575024 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Acute Kidney Injury Due to Sepsis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05575024 currently recruiting?

Yes, NCT05575024 is actively recruiting participants. Contact the research team at hansway7@snu.ac.kr for enrollment information.

Where is the NCT05575024 trial being conducted?

This trial is being conducted at Seoul, South Korea.

Who is sponsoring the NCT05575024 clinical trial?

NCT05575024 is sponsored by Seoul National University Hospital. The principal investigator is Seung Seok Han, M.D. at Seoul National University Hospital. The trial plans to enroll 98 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology