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Recruiting NCT05575024
Hemodynamic Stability in Septic Shock Patients Undergoing Continuous Renal Replacement Therapy With oXiris Membrane
Trial Parameters
Condition Acute Kidney Injury Due to Sepsis
Sponsor Seoul National University Hospital
Study Type OBSERVATIONAL
Phase N/A
Enrollment 98
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2024-01-01
Completion 2026-06-30
Interventions
oXiris membranePolysulfone membrane
Brief Summary
The new adsorbing membrane for continuous renal replacement therapy (CRRT), oXiris, can reduce plasma cytokines and endotoxins in septic shock patients with severe acute kidney injury, compared with standard membranes. However, its hemodynamic stability or benefits have not been thoroughly evaluated although this is reasonable.
Eligibility Criteria
Inclusion Criteria: * Aged ≥ 18 years * Sepsis related acute kidney injury requiring continuous renal replacement therapy Exclusion Criteria: • No monitoring of blood pressure and ECG