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Recruiting NCT06593717

NCT06593717 Hemodynamic Monitoring and Fluid Responsiveness in Venovenous Extracorporeal Membrane Oxygenation (VV ECMO) - "HemodynamECMOnitoring-VV Study"

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Clinical Trial Summary
NCT ID NCT06593717
Status Recruiting
Phase
Sponsor Medical University of Vienna
Condition ECMO Treatment
Study Type INTERVENTIONAL
Enrollment 30 participants
Start Date 2024-05-03
Primary Completion 2027-01

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 75 Years
Study Type INTERVENTIONAL
Interventions
Transthoracic EchocardiographyUncalibrated Pulse Contour AnalysisTranspulmonary Thermodilution/Calibrated Pulse Contour Analysis

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 30 participants in total. It began in 2024-05-03 with a primary completion date of 2027-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

In extracorporeal membrane oxygenation (ECMO), blood is drawn out of the body via tubes, oxygenated in an artificial lung; and then pumped back into the blood vessels. This allows the supply of oxygen-rich blood to the organs (brain, heart, lungs, kidneys, liver, intestines, etc.) to be maintained. Continuous monitoring of cardiac function and circulatory status (blood pressure, blood flow to organs) is very important in intensive care medicine in order to control the administration of circulation-supporting medication and infusions. Various devices are routinely used for this task. However, in the specific situation of ECMO treatment, the measurements of these devices could be affected due to the artificial circulation; outside the body. The purpose of this study is therefore to test the accuracy of different methods of circulation monitoring during ECMO treatment.

Eligibility Criteria

Inclusion Criteria: * Patient receiving VV-ECMO support * Age 18 - 75 years Exclusion Criteria: * Pregnancy * Conditions not allowing for passive leg raising maneuvers, e.g. "open abdomen", known or suspected elevation of intracranial pressure, recent leg or spinal trauma or orthopedic conditions not permitting leg raising * Known ischemic or hemorrhagic stroke within 3 months prior to study enrollment. Suspicion of raised intracranial pressure is defined as pupil divergence (if not yet further clarified radiographically/neurologically/ophthalmologically) or signs detected in routine computed tomography scans (compressed or elapsed basal cisterns or midline shift \> 5 mm.

Contact & Investigator

Central Contact

Bernhard Nagler, MD

✉ bernhard.nagler@meduniwien.ac.at

📞 +4314040044920

Frequently Asked Questions

Who can join the NCT06593717 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 75 Years, studying ECMO Treatment. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06593717 currently recruiting?

Yes, NCT06593717 is actively recruiting participants. Contact the research team at bernhard.nagler@meduniwien.ac.at for enrollment information.

Where is the NCT06593717 trial being conducted?

This trial is being conducted at Vienna, Austria.

Who is sponsoring the NCT06593717 clinical trial?

NCT06593717 is sponsored by Medical University of Vienna. The trial plans to enroll 30 participants.

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