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Recruiting NCT05669183

Hemodynamic Comparison of Peripheral and Central VA ECMO.

Trial Parameters

Condition Shock, Cardiogenic
Sponsor First Affiliated Hospital Xi'an Jiaotong University
Study Type OBSERVATIONAL
Phase N/A
Enrollment 136
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2023-08-12
Completion 2024-10-30
Interventions
Veno-arterial extracorporeal membrane oxygenation

Brief Summary

The goal of this clinical trial is to monitor hemodynamic differences between central veno-arterial extracorporeal membrane oxygenation (VA ECMO) and peripheral VA ECMO. The main question it aims to answer is: * Efficacy of the different cannulation strategies for the establishment of for VA-ECMO circulation on hemodynamics and organ perfusion. Participants require VA ECMO support, will be divided into two groups in an intention-to-treat analysis: central artery cannulation and peripheral artery cannulation. Researchers will analyze different cannulation strategies for VA-ECMO and identify potential advantages and disadvantages for two groups of VA-ECMO.

Eligibility Criteria

Inclusion Criteria: * Age≥18 years * Participants with cardiogenic shock * Obtaining informed consent from participants or their affiliated beneficiaries Exclusion Criteria: * Irreversible heart failure * Contraindications to anticoagulation therapy * Uncontrolled bleeding * Irreversible neurological pathology * Participants limited to extracorporeal cardiopulmonary resuscitation

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