NCT07726251 Hemodynamic Changes and Trigeminocardiac Reflex During Bimaxillary Orthognathic Surgery
| NCT ID | NCT07726251 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Kırıkkale University |
| Condition | Orthognathic Surgery |
| Study Type | OBSERVATIONAL |
| Enrollment | 18 participants |
| Start Date | 2026-06-20 |
| Primary Completion | 2027-06-20 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 18 participants in total. It began in 2026-06-20 with a primary completion date of 2027-06-20.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This observational study aims to evaluate hemodynamic changes occurring during bimaxillary orthognathic surgery using routinely collected intraoperative monitoring data. Heart rate, systolic and diastolic blood pressure, mean arterial pressure, and oxygen saturation will be recorded during different stages of surgery as part of standard clinical care. The study will also evaluate the occurrence of the trigeminocardiac reflex (TCR) and its association with patient characteristics and surgical stages. No additional interventions, laboratory tests, or procedures will be performed beyond routine clinical practice. The findings may contribute to the early recognition and management of intraoperative hemodynamic changes during orthognathic surgery.
Eligibility Criteria
Inclusion Criteria: * Adults aged 18 to 40 years. Patients with an indication for bimaxillary orthognathic surgery. Patients with complete intraoperative routine hemodynamic monitoring data recorded during surgery. Patients who provide written informed consent to participate in the study. Exclusion Criteria: * Patients without an indication for bimaxillary orthognathic surgery. Individuals younger than 18 years or older than 40 years. Patients with known cardiovascular diseases, including arrhythmia, heart failure, coronary artery disease, or other significant cardiovascular disorders. Patients with systemic diseases, including diabetes mellitus, hypertension, thyroid disorders, or other significant systemic conditions. Patients with a diagnosed psychiatric disorder. Patients with incomplete or irregularly recorded intraoperative hemodynamic monitoring data. Individuals who decline to participate in the study or do not provide written informed consent.
Contact & Investigator
Elif Çoban, DDS
PRINCIPAL INVESTIGATOR
Kırıkkale University Faculty of Dentistry
Frequently Asked Questions
Who can join the NCT07726251 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 40 Years, studying Orthognathic Surgery. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07726251 currently recruiting?
Yes, NCT07726251 is actively recruiting participants. Contact the research team at elifcoban@kku.edu.tr for enrollment information.
Where is the NCT07726251 trial being conducted?
This trial is being conducted at Kirikkale, Turkey (Türkiye).
Who is sponsoring the NCT07726251 clinical trial?
NCT07726251 is sponsored by Kırıkkale University. The principal investigator is Elif Çoban, DDS at Kırıkkale University Faculty of Dentistry. The trial plans to enroll 18 participants.