NCT07847424 Heat Therapy During Reduced Physical Activity
| NCT ID | NCT07847424 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Brigham Young University |
| Condition | Physical Inactivity |
| Study Type | INTERVENTIONAL |
| Enrollment | 60 participants |
| Start Date | 2026-01-01 |
| Primary Completion | 2027-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 60 participants in total. It began in 2026-01-01 with a primary completion date of 2027-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of this randomized controlled trial is to determine whether daily Finnish dry sauna therapy attenuates the adverse cardiovascular, muscular, and metabolic effects of seven days of experimentally reduced physical activity in healthy adults. Participants will be randomized to one of three groups: (1) maintained habitual physical activity with daily sauna therapy, (2) reduced physical activity with daily room-temperature sauna visits (control), or (3) reduced physical activity with daily sauna therapy. Reduced physical activity will be achieved by decreasing daily step count to approximately 1,000 steps per day with the assistance of a power wheelchair. Outcome measures include vascular endothelial function, exercise tolerance, muscle protein synthesis, body composition, blood pressure, glucose regulation, and physiological responses to heat exposure. The study will determine whether passive heat therapy can serve as a practical intervention to preserve cardiometabolic health during short periods of reduced mobility.
Eligibility Criteria
Inclusion Criteria: * Adults aged 18 years or older * Healthy men and premenopausal women * Able and willing to provide written informed consent * Able to perform knee-extension cycling exercise * Stable habitual physical activity for at least 3 months before enrollment * Pass the American College of Sports Medicine (ACSM) Preparticipation Health Screening * Not currently taking medications known to affect cardiovascular function (e.g., antihypertensive medications or beta-blockers) * No regular sauna or hot-tub use (fewer than six exposures during the previous 2 months) * Willing and able to comply with all study procedures, including temporary reduction of physical activity, daily sauna visits, physiological testing, and follow-up assessments Exclusion Criteria: * Younger than 18 years of age * Failure to pass the ACSM Preparticipation Health Screening * Unable or unwilling to perform exercise testing * Current cigarette or marijuana use * Pregnant or planning to become pregnant during the study * History or current diagnosis of cardiovascular disease, metabolic disease, or cognitive impairment * Use of medications known to influence cardiovascular function or exercise tolerance (e.g., antihypertensive medications or beta-blockers) * Regular sauna or hot-tub use (six or more exposures during the previous 2 months) * History of heat-related illness * Any condition that, in the opinion of the investigators, would interfere with safe participation or interpretation of study results * Inability to understand the study procedures or provide informed consent
Contact & Investigator
Robert D Hyldahl, PhD
PRINCIPAL INVESTIGATOR
Brigham Young University
Frequently Asked Questions
Who can join the NCT07847424 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Physical Inactivity. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07847424 currently recruiting?
Yes, NCT07847424 is actively recruiting participants. Contact the research team at robhyldahl@byu.edu for enrollment information.
Where is the NCT07847424 trial being conducted?
This trial is being conducted at Provo, United States.
Who is sponsoring the NCT07847424 clinical trial?
NCT07847424 is sponsored by Brigham Young University. The principal investigator is Robert D Hyldahl, PhD at Brigham Young University. The trial plans to enroll 60 participants.