NCT07634640 Hearts on Fire: Targeting Inflammation in Heart Failure With Preserved Ejection Fraction
| NCT ID | NCT07634640 |
| Status | Recruiting |
| Phase | EARLY_Phase 1 |
| Sponsor | University of Florida |
| Condition | Heart Failure With Preserved Ejection Fraction (HFPEF) |
| Study Type | INTERVENTIONAL |
| Enrollment | 70 participants |
| Start Date | 2023-11-03 |
| Primary Completion | 2027-05-31 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
Phase 1 is the earliest stage of human testing — safety and dosage are the primary focus. Visits are frequent and medical supervision is intensive. You will be among the first people to receive this treatment.
This trial targets 70 participants in total. It began in 2023-11-03 with a primary completion date of 2027-05-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Subjects undergo a gadolinium-based CMR followed by an iron infusion and then a repeat CMR in 72 hours
Eligibility Criteria
Inclusion Criteria: * HFpEF Exclusion Criteria: * Renal insufficiency
Contact & Investigator
Ellen C Keeley, MD, MS
PRINCIPAL INVESTIGATOR
University of Florida
Frequently Asked Questions
Who can join the NCT07634640 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 85 Years, studying Heart Failure With Preserved Ejection Fraction (HFPEF). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
What phase is the NCT07634640 trial and what does that mean for participants?
Phase 1 trials are the first stage of human testing. The primary goal is to assess safety and determine appropriate dosage levels. Participants are closely monitored. These trials typically involve a small number of volunteers.
Is NCT07634640 currently recruiting?
Yes, NCT07634640 is actively recruiting participants. Contact the research team at ellen.keeley@medicine.ufl.edu for enrollment information.
Where is the NCT07634640 trial being conducted?
This trial is being conducted at Gainesville, United States.
Who is sponsoring the NCT07634640 clinical trial?
NCT07634640 is sponsored by University of Florida. The principal investigator is Ellen C Keeley, MD, MS at University of Florida. The trial plans to enroll 70 participants.
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