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Recruiting NCT07488338

NCT07488338 HABIT-ILE + FST in Children With SMA: Preliminary Effectiveness

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Clinical Trial Summary
NCT ID NCT07488338
Status Recruiting
Phase
Sponsor Teachers College, Columbia University
Condition Spinal Muscular Atrophy (SMA)
Study Type INTERVENTIONAL
Enrollment 20 participants
Start Date 2026-03-15
Primary Completion 2028-02-28

Eligibility & Interventions

Sex All sexes
Min Age 5 Years
Max Age 17 Years
Study Type INTERVENTIONAL
Interventions
Combined Hand-Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE) + functional strength training (FST)

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 20 participants in total. It began in 2026-03-15 with a primary completion date of 2028-02-28.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This single-arm pilot study will assess the preliminary effectiveness of an intensive motor skill intervention (HABIT-ILE) combined with functional strength training (FST) in children with SMA who are receiving disease-modifying therapies. Participants will attend a HABIT-ILE + FST summer camp for 6 hours per day over a 3-week period, totaling 90 hours of training.

Eligibility Criteria

Inclusion Criteria: * Have a confirmed SMA diagnosis * Be 5-17 years old * Complete all pre- and post-intervention assessments * Understand and speak English * Follow instructions without major cognitive or behavioral issues * Have received a stable disease-modifying therapy (DMT) dose for ≥6 months * Be classified as a sitter or walker (SMA type 2 or 3) with supported standing ability (score ≥1 on Item 18 of the HFMSE) without KAFOs, AFOs, or external standing devices Exclusion Criteria: * Orthopedic surgery within the past year * New pharmaceutical treatment during the study * Concurrent participation in another clinical trial

Contact & Investigator

Central Contact

Andrew M Gordon, PhD

✉ ag275@tc.columbia.edu

📞 +1(212) 678-3332

Frequently Asked Questions

Who can join the NCT07488338 clinical trial?

This trial is open to participants of all sexes, aged 5 Years or older, up to 17 Years, studying Spinal Muscular Atrophy (SMA). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT07488338 currently recruiting?

Yes, NCT07488338 is actively recruiting participants. Contact the research team at ag275@tc.columbia.edu for enrollment information.

Where is the NCT07488338 trial being conducted?

This trial is being conducted at New York, United States.

Who is sponsoring the NCT07488338 clinical trial?

NCT07488338 is sponsored by Teachers College, Columbia University. The trial plans to enroll 20 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology