NCT06637657 Guided Optimisation of Long-term Disease rEduction in secoNdary Prevention of CVD
| NCT ID | NCT06637657 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) |
| Condition | Acute Coronary Syndrome |
| Study Type | OBSERVATIONAL |
| Enrollment | 5,586 participants |
| Start Date | 2024-07-09 |
| Primary Completion | 2029-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 5,586 participants in total. It began in 2024-07-09 with a primary completion date of 2029-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this observational study is to evaluate the implementation of a 'first-time-right' pharmacological treatment strategy in patients hospitalized with coronary artery disease. The main question it aims to answer is: Does early (immediately post-event) initiation of a full set of guideline-based, individualized, preventive medication lead to reductions in cardiovascular events compared to current practice (incremental titration strategies)? Researchers will compare the 'first-time-right' strategy group to the current practice group to see if there are improvements in major adverse cardiac and cerebrovascular events (MACE) at 36 months. Participants will: * Receive either the 'first-time-right' strategy or current practice for secondary prevention. * Be monitored (data collection) through routine clinical visits at baseline, 8 weeks, 12, and additional telephone contacts at 24, and 36 months after discharge. * Complete online questionnaires at hospitalization, 8 weeks, 12, 24, and 36 months after discharge.
Eligibility Criteria
Inclusion Criteria: * \>18 years of age (no upper limit) * Coronary event, i.e. ACS or coronary revascularisation * Able to provide informed consent Exclusion Criteria: * (short-term planned) pregnancy or breast feeding * Dialysis
Contact & Investigator
Marjolein Snaterse, dr.
STUDY CHAIR
Amsterdam UMC
Frequently Asked Questions
Who can join the NCT06637657 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Acute Coronary Syndrome. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06637657 currently recruiting?
Yes, NCT06637657 is actively recruiting participants. Contact the research team at m.vandenbogaart@amsterdamumc.nl for enrollment information.
Where is the NCT06637657 trial being conducted?
This trial is being conducted at Amsterdam, Netherlands.
Who is sponsoring the NCT06637657 clinical trial?
NCT06637657 is sponsored by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA). The principal investigator is Marjolein Snaterse, dr. at Amsterdam UMC. The trial plans to enroll 5,586 participants.