NCT07451873 Glycocalyx and Oxidative Stress in Endothelial Function (Part 2)
| NCT ID | NCT07451873 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Josip Juraj Strossmayer University of Osijek |
| Condition | Coronary Heart Disease |
| Study Type | OBSERVATIONAL |
| Enrollment | 35 participants |
| Start Date | 2025-10-01 |
| Primary Completion | 2029-09-30 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 35 participants in total. It began in 2025-10-01 with a primary completion date of 2029-09-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The primary research objective of the project is to determine the role of eGC in microvascular reactivity in patients with coronary heart disease (CHD) before and after bypass grafting (cross-sectional study 2).The main objective of the project is to increase the excellence and interdisciplinarity of scientific work at MEFOS by connecting researchers from different scientific fields, improving conditions and resources for scientific work, and increasing international cooperation, in line with strategic objective 1: raising scientific excellence. The results of the project could provide pathophysiological insight into the development and maintenance of endothelial dysfunction in CVD, as well as identify new biomarkers for CVD.
Eligibility Criteria
Inclusion Criteria: * adult patients of both sexes over 18 years of age * Caucasian * undergoing elective coronary artery bypass grafting (CABG) * provided written informed consent Exclusion Criteria: * emergency surgery * sepsis or severe systemic inflammation before surgery * severe renal or hepatic insufficiency * immunosuppression * serious comorbidities (e.g., active cancer) * therapies that could affect oxidative stress (e.g., high doses of corticosteroids)
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07451873 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Coronary Heart Disease. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07451873 currently recruiting?
Yes, NCT07451873 is actively recruiting participants. Contact the research team at ines.drenjancevic@mefos.hr for enrollment information.
Where is the NCT07451873 trial being conducted?
This trial is being conducted at Osijek, Croatia.
Who is sponsoring the NCT07451873 clinical trial?
NCT07451873 is sponsored by Josip Juraj Strossmayer University of Osijek. The trial plans to enroll 35 participants.