NCT06000865 Glaucoma Rehabilitation With Action viDeo Games and Exercise - GRADE
| NCT ID | NCT06000865 |
| Status | Recruiting |
| Phase | — |
| Sponsor | The Hong Kong Polytechnic University |
| Condition | Glaucoma |
| Study Type | INTERVENTIONAL |
| Enrollment | 56 participants |
| Start Date | 2023-09-09 |
| Primary Completion | 2025-07-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 56 participants in total. It began in 2023-09-09 with a primary completion date of 2025-07-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Falls are one of the most serious public health concerns for seniors, with significant medical and economic consequences. This concern is even higher in patients with peripheral field loss due to glaucoma because of the patients' compromised visual input. The investigators' project proposes an innovative, entertaining, easily accessible and enjoyable intervention for improving mobility and postural control function in glaucoma patients with peripheral vision loss, who are more prone to falls and suffer from fear of falling. The new intervention examined in this project can be implemented in current vision and balance rehabilitation programs, and may benefit patients with different types of visual impairment to minimize their risk of falls and improve their quality of life.
Eligibility Criteria
Inclusion Criteria: 1. Presence of moderate to severe bilateral glaucomatous optic neuropathy (GON) from primary open-angle (including normal tension) or angle-closure glaucoma, as determined by an ophthalmologist, with abnormal Glaucoma Hemifield Test on standard Humphrey Field Analyzer 24-2 testing and matching nerve-fiber layer thinning on optical coherence tomography; 2. Stable vision and visual field loss for at least 3 months; 3. With a best-corrected distance acuity of 6/12 or better (equivalent to 0.3 logMAR acuity or better to confirm that participant's central vision is preserved); 4. With a cognitive functional score of 22 or above in the Montreal Cognitive Assessment - Hong Kong version (to confirm participants' intact cognitive function). Exclusion Criteria: 1. Advanced glaucoma with GON of median deviation worse than -25 decibel; 2. Ocular diseases other than glaucoma (e.g., age-related macular degeneration, diabetic retinopathy, and moderate to severe cataract); 3. Severe medical problems (e.g., stroke, Parkinson's disease) or self-reported neurological (e.g. brain surgery, brain tumor and peripheral neuropathy), or cognitive disorders (e.g., diagnosed dementia or cognitive impairment); 4. Physical impairments (e.g. need the use of orthopedic and mobility aids) or physical limitations restricting them from independent walking; 5. Self-reported or medically diagnosed vestibular/ cerebellar dysfunction, history of vertigo, or severe hearing loss; 6. Using any medications for any neurological conditions or psychiatric drugs (e.g. sedative, hypnotic) that might interfere motor control; and 7. Currently attending any intensive physical/balance training.
Contact & Investigator
Allen Cheong, PhD
PRINCIPAL INVESTIGATOR
The Hong Kong Polytechnic University
Frequently Asked Questions
Who can join the NCT06000865 clinical trial?
This trial is open to participants of all sexes, aged 55 Years or older, up to 80 Years, studying Glaucoma. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06000865 currently recruiting?
Yes, NCT06000865 is actively recruiting participants. Contact the research team at allen.my.cheong@polyu.edu.hk for enrollment information.
Where is the NCT06000865 trial being conducted?
This trial is being conducted at Hong Kong, Hong Kong.
Who is sponsoring the NCT06000865 clinical trial?
NCT06000865 is sponsored by The Hong Kong Polytechnic University. The principal investigator is Allen Cheong, PhD at The Hong Kong Polytechnic University. The trial plans to enroll 56 participants.