| NCT ID | NCT07857460 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University Hospital Augsburg |
| Condition | Hypoparathyroidism |
| Study Type | OBSERVATIONAL |
| Enrollment | 150 participants |
| Start Date | 2021-07-06 |
| Primary Completion | 2036-02-01 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 150 participants in total. It began in 2021-07-06 with a primary completion date of 2036-02-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Chronic hypoparathyroidism is a rare condition in which the parathyroid glands do not make enough parathyroid hormone (PTH). PTH helps control the levels of calcium and phosphate in the blood. When there is not enough PTH, calcium levels can become too low and phosphate levels can become too high. This may cause symptoms such as tingling, muscle cramps, weakness, or other health problems. The most common cause of chronic hypoparathyroidism is surgery in the neck area. It can happen after thyroid surgery, surgery on the parathyroid glands, or other operations in the neck. At the moment, most patients are treated with calcium and vitamin D tablets. These treatments help control calcium levels, but they cannot fully replace the normal effects of PTH in the body. A medicine that contains a form of human PTH is available for some patients, but it is not yet the standard treatment for everyone. This registry collects medical information and follows patients over time. Its aim is to better understand patients' symptoms, possible long-term health problems, treatments, and overall health. A group of patients who have had their thyroid removed but do not have hypoparathyroidism will also be included for comparison.
Eligibility Criteria
Inclusion Criteria: * diagnosis of chronic hypo- or pseudohypoparathyroidism \> 6 months or diagnosis of pseudohypoparathyroidism * age \>= 18 yrs. * residing in Germany * Written consent for patients capable of giving informed consent Exclusion Criteria: * Minors and patients with severe mental illnesses, or patients who are unable to provide written informed consent. Controll group * h/o thyroidektomy with thyroid hormone replacement * age \>= 18 yrs. * residing in Germany * The exclusion criteria also apply to this group.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07857460 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Hypoparathyroidism. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07857460 currently recruiting?
Yes, NCT07857460 is actively recruiting participants. Contact the research team at endokrinologie@uk-augsburg.de for enrollment information.
Where is the NCT07857460 trial being conducted?
This trial is being conducted at Augsburg, Germany.
Who is sponsoring the NCT07857460 clinical trial?
NCT07857460 is sponsored by University Hospital Augsburg. The trial plans to enroll 150 participants.