NCT03713853 Geriatric Acetabular fracTures: Open Reduction Internal Fixation Versus Replacement
| NCT ID | NCT03713853 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Unity Health Toronto |
| Condition | Acetabular Fracture |
| Study Type | OBSERVATIONAL |
| Enrollment | 104 participants |
| Start Date | 2026-12 |
| Primary Completion | 2029-12 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 104 participants in total. It began in 2026-12 with a primary completion date of 2029-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Management of acetabular (hip) fractures in the geriatric population can be very challenging because of pre-existing medical comorbidities, pre-existing osteoporosis and increased risk of mortality. The two most common treatment options for acetabular fractures are either surgical fixation using plates and screws to hold the fractured pieces in the correct position until the fracture has healed or surgical fixation in addition to a total hip replacement. Surgical fixation requires prolonged immobilization of the affected limb (typically around 6-12 weeks post-operatively), which can lead to disability and other complications. Such patients, especially those who are frail and cognitively impaired, are unable to adhere to the immobilization restrictions, leading to an increased risk of fixation failure. Patients who underwent open reduction internal fixation (ORIF) of an acetabular fracture were reported to have about 25 times greater incidence of hip replacement compared with general population matched controls. Additionally, performing a subsequent hip replacement after a previous surgical fixation (ORIF) of an acetabular fracture, especially in the elderly population, can present a number of technical difficulties including; difficult dissection due to previous incision(s) and scarring, dealing with retained hardware, bony deficiency and the possibility of infected hardware. The aim of the study is to perform a large cohort study to assess pain and physical function in patients 60 years and older who have sustained an acetabular fracture.
Eligibility Criteria
Inclusion Criteria: * 60 years of age or older * Isolated and Displaced (more or equal to 2mm on any radiographic view) fracture of the acetabulum * Patient requires surgical treatment, either THA+ORIF or ORIF surgeries * Fracture is acute (within 3 weeks of injury) * Patient was ambulatory (with or without walking aids) prior to their acetabular fracture injury * Patient is able to provide informed consent to participation in the study * Patient is able to read and understand English Exclusion Criteria: * Presence of an active or chronic infection around the fracture (soft tissue or bone) * Open/compound fracture * Bilateral acetabular fractures * Pathological fracture excluding osteoporosis * Periprosthetic fracture (previous arthroplasty or hardware or ORIF in-situ). Hardware (screws or plates or nails or hemi-arthroplasty) on the femoral side are not excluded. * Medical or surgical contraindication to surgery * Dementia
Contact & Investigator
Amir Khoshbin, MD
PRINCIPAL INVESTIGATOR
Unity Health Toronto
Frequently Asked Questions
Who can join the NCT03713853 clinical trial?
This trial is open to participants of all sexes, aged 60 Years or older, studying Acetabular Fracture. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT03713853 currently recruiting?
Yes, NCT03713853 is actively recruiting participants. Contact the research team at cassandra.tardif-theriault@unityhealth.to for enrollment information.
Where is the NCT03713853 trial being conducted?
This trial is being conducted at Toronto, Canada.
Who is sponsoring the NCT03713853 clinical trial?
NCT03713853 is sponsored by Unity Health Toronto. The principal investigator is Amir Khoshbin, MD at Unity Health Toronto. The trial plans to enroll 104 participants.