NCT04772963 Genetics of Central Nervous System Arteriovenous Malformations (GENE-MAV)
| NCT ID | NCT04772963 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Fondation Ophtalmologique Adolphe de Rothschild |
| Condition | Arteriovenous Malformations |
| Study Type | OBSERVATIONAL |
| Enrollment | 300 participants |
| Start Date | 2022-02-17 |
| Primary Completion | 2026-03 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 300 participants in total. It began in 2022-02-17 with a primary completion date of 2026-03.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Cerebral and medullary arteriovenous malformations (AVMs) lead to arterial and venous networks to communicate pathologically, creating an arteriovenous shunt. The occurrence of intracranial haemorrhage is the most important prognostic factor of AVMs because it is associated with a significant morbidity and mortality. The genetic, molecular and cellular mechanisms that cause vascular malformations of the central nervous system are partially known and the influence of genetic damage on the prognosis of AVMs is poorly known.
Eligibility Criteria
Inclusion Criteria: * Patient with a vascular malformation of the cerebral or medullary identified on diagnostic imaging (angio-CT, angio-MRI or diagnostic angiography) for which clinical monitoring alone or intervention (endovascular treatment, surgery or radiosurgery) is planned in the centres participating in the research. Exclusion Criteria: * Pregnant, parturient or breastfeeding woman
Contact & Investigator
Stanislas Smajda, MD
PRINCIPAL INVESTIGATOR
Fondation Ophtalmologique Adolphe de Rothschild
Frequently Asked Questions
Who can join the NCT04772963 clinical trial?
This trial is open to participants of all sexes, studying Arteriovenous Malformations. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04772963 currently recruiting?
Yes, NCT04772963 is actively recruiting participants. Contact the research team at ssmajda@for.paris for enrollment information.
Where is the NCT04772963 trial being conducted?
This trial is being conducted at Paris, France.
Who is sponsoring the NCT04772963 clinical trial?
NCT04772963 is sponsored by Fondation Ophtalmologique Adolphe de Rothschild. The principal investigator is Stanislas Smajda, MD at Fondation Ophtalmologique Adolphe de Rothschild. The trial plans to enroll 300 participants.