NCT06329739 Genetics in Parkinson's Disease: Behavioral and Cognitive Outcomes
| NCT ID | NCT06329739 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico |
| Condition | Parkinson Disease |
| Study Type | OBSERVATIONAL |
| Enrollment | 68 participants |
| Start Date | 2021-12-14 |
| Primary Completion | 2031-12-14 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 68 participants in total. It began in 2021-12-14 with a primary completion date of 2031-12-14.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The genetic landscape of Parkinson's disease (PD) is characterised by rare high penetrance pathogenic variants causing familial disease, genetic risk factor variants driving PD risk in a significant minority in PD cases and high frequency, low penetrance variants, which contribute a small increase of the risk of developing sporadic PD. This knowledge has the potential to have a major impact in the clinical care of people with PD. The goal of this observational study is to evaluate the impact of genetic mutation on behavior and cognition in PD patients. Patients will be assessed over time using test, questionnaire and standardised clinica scales. An initial assessment and annual follow-up assessments will be carried out for 5 years. Researchers will compare data collected from patients with genetic mutation versus patients without mutation.
Eligibility Criteria
Inclusion Criteria: * diagnosed with Parkinson's Disease (PD) * in use of dopaminergic medication (L-Dopa and/or dopamine agonists) * genetic testing for mendelian forms of PD * able to provide informed consent to participate in the study Exclusion Criteria: * Patients underwent Deep Brain Stimulation (DBS) treatment
Contact & Investigator
Francesca Mameli, Dr
PRINCIPAL INVESTIGATOR
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Frequently Asked Questions
Who can join the NCT06329739 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Parkinson Disease. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06329739 currently recruiting?
Yes, NCT06329739 is actively recruiting participants. Contact the research team at francesca.mameli@policlinico.mi.it for enrollment information.
Where is the NCT06329739 trial being conducted?
This trial is being conducted at Milan, Italy.
Who is sponsoring the NCT06329739 clinical trial?
NCT06329739 is sponsored by Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico. The principal investigator is Francesca Mameli, Dr at Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico. The trial plans to enroll 68 participants.
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