NCT04770519 Genetic Studies of Strabismus, Nystagmus, and Associated Disorders
| NCT ID | NCT04770519 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Boston Children's Hospital |
| Condition | Strabismus |
| Study Type | OBSERVATIONAL |
| Enrollment | 400 participants |
| Start Date | 2021-09-03 |
| Primary Completion | 2030-12 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 400 participants in total. It began in 2021-09-03 with a primary completion date of 2030-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Strabismus (misalignment of the eyes) often runs in families. In this study, the investigators are looking for genetic variants associated with strabismus and nystagmus. Three types of subects will be enrolled: (1) Families with at least 3 members with strabismus, (2) individuals with infantile esotropia and their parents and siblings, and (3) individuals with infantile nystagmus and their parents. Whole exome and/or whole genome sequencing will be used to identify genetic variants shared by family members with strabismus and to identify genetic causes of nystagmus.
Eligibility Criteria
Inclusion Criteria: \- Member of a family with at least 3 biological relatives with strabismus. (Both affected and non-affected family members will be enrolled). OR \- Member of a family with at least 1 individual with infantile esotropia. (Both affected and non-affected family members will be enrolled). OR \- Member of a family with at least 1 individual with infantile nystagmus. (Both affected and non-affected family members will be enrolled). Exclusion Criteria: * paralytic strabismus in affected family members
Contact & Investigator
Mary Whitman, MD/PhD
PRINCIPAL INVESTIGATOR
Assistant Professor
Frequently Asked Questions
Who can join the NCT04770519 clinical trial?
This trial is open to participants of all sexes, studying Strabismus. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04770519 currently recruiting?
Yes, NCT04770519 is actively recruiting participants. Contact the research team at research.whitman@childrens.harvard.edu for enrollment information.
Where is the NCT04770519 trial being conducted?
This trial is being conducted at Boston, United States.
Who is sponsoring the NCT04770519 clinical trial?
NCT04770519 is sponsored by Boston Children's Hospital. The principal investigator is Mary Whitman, MD/PhD at Assistant Professor. The trial plans to enroll 400 participants.