NCT06896266 Genetic Characterization of Patients With Arrhythmia-Induced Cardiomyopathy
| NCT ID | NCT06896266 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Hospital Universitario 12 de Octubre |
| Condition | Arrhythmia |
| Study Type | OBSERVATIONAL |
| Enrollment | 109 participants |
| Start Date | 2024-12-01 |
| Primary Completion | 2025-12 |
Trial Parameters
Eligibility Fast-Check
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Brief Summary
The goal of this observational study is to learn about the genetic insights of arrhythmya-induced cardiomyopathy and its clinical prognosis. The main questions it aims to answer are: I. Does patients with arrhythmia-induced cardiomyopathy have a greater proportion of genetic mutations compared with other types of cardiomyopathy or general population? II. Have the genetics any prognostic impact in patients with arrhythmia-induced cardiomyopathy?
Eligibility Criteria
Inclusion Criteria: * Presence of atrial fibrillation or atrial flutter not self-limited. * Performance of a cardiac imaging test with systolic function analysis (echocardiogram, magnetic resonance, CT scan) during the clinical course of the arrhythmia, exhibiting a left ventricular ejection fraction (LVEF) \<50%. In order for the test to be representative, the maximum time between the performance of the imaging test and the rhythm control procedure will be 3 months, in the absence of intervening cardiovascular events that may have caused a variation in LVEF. In the event that the patient had a previously known LVEF \<50%, the change with respect to this attributable to tachyarrhythmia has to be ≥10%. * Signature of informed consent. * Ability to understand and accept participation in the study. Exclusion Criteria: * Refusal of informed consent. * Legal or juridical incapacity. * Age \<18 years. * Life expectancy less than 1 year. * Impossibility of a follow-up of at least 6 months. *