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Recruiting NCT03054584

NCT03054584 Genetic Basis of Melanocytic Nevi

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Clinical Trial Summary
NCT ID NCT03054584
Status Recruiting
Phase
Sponsor University of California, Davis
Condition Melanocytic Nevi
Study Type OBSERVATIONAL
Enrollment 50 participants
Start Date 2017-06-26
Primary Completion 2028-06

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL
Interventions
Collecting Nevi

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 50 participants in total. It began in 2017-06-26 with a primary completion date of 2028-06.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The objective of this protocol is to further elucidate the genetic mutations that drive melanocytic nevi (benign melanocytic neoplasms, moles). This will be performed by whole genome, whole exome, or targeted sequencing of de-identified specimens. Herein, the investigators plan to isolate DNA from de-identified skin biopsy specimens and blood samples: 1. From melanocytic nevi collected by skin biopsy (a shave or punch biopsy). A part of the tissue will be submitted for routine diagnostic dermatopathology and investigational histomorphologic and immunohistochemical analysis. 2. From corresponding normal tissue (blood). DNA isolated from blood will be used as a normal control when analyzing sequencing data to identify somatic mutations in lesional tissue.

Eligibility Criteria

Inclusion criteria: * Male or female subjects that are 18 years or older * Subjects with melanocytic nevi\\ Exclusion criteria: * Patients less than 18 years of age * Patients without melanocytic nevi * Patients with a bleeding disorder or are taking anticoagulation medication

Contact & Investigator

Central Contact

Maija Kiuru, MD

✉ mkiuru@ucdavis.edu

📞 916-734-0591

Frequently Asked Questions

Who can join the NCT03054584 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Melanocytic Nevi. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT03054584 currently recruiting?

Yes, NCT03054584 is actively recruiting participants. Contact the research team at mkiuru@ucdavis.edu for enrollment information.

Where is the NCT03054584 trial being conducted?

This trial is being conducted at Sacramento, United States.

Who is sponsoring the NCT03054584 clinical trial?

NCT03054584 is sponsored by University of California, Davis. The trial plans to enroll 50 participants.

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