NCT06353607 Genetic Architecture of Acute Aortic Syndromes and Aortic Aneurysm.
| NCT ID | NCT06353607 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University Hospital, Basel, Switzerland |
| Condition | Acute Aortic Dissection |
| Study Type | OBSERVATIONAL |
| Enrollment | 730 participants |
| Start Date | 2024-04-08 |
| Primary Completion | 2028-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 730 participants in total. It began in 2024-04-08 with a primary completion date of 2028-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The aim of this study is to explore the genetic information associated with the development of TAA and aAD in individuals without history or syndromic features (Marfan syndrome, Ehlers-Danlos syndrome, Turner syndrome etc.) for aortic disease. For this purpose, whole genome sequencing will be performed in patients with documented aortic aneurysm or/and aortic dissection.
Eligibility Criteria
Inclusion Criteria: * All adult patients \> 18 years who underwent surgery for aAD or TAA intervention at the University Hospital Basel, starting in 2015. * All patients who will undergo surgery for aAD or TAA at the University Hospital Basel, beginning in 2024. Exclusion Criteria: * Patients will be excluded if they are not able or not willing to provide informed consent. * Patients with diagnosed heritable vascular disorders, such as Marfan syndrome, Turner Syndrome, Loeyes Dietz and Ehlers-Danlos syndrome.
Contact & Investigator
Denis Berdajs, Prof. Dr.
PRINCIPAL INVESTIGATOR
University Hospital, Basel, Switzerland
Frequently Asked Questions
Who can join the NCT06353607 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Acute Aortic Dissection. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06353607 currently recruiting?
Yes, NCT06353607 is actively recruiting participants. Contact the research team at denis.berdajs@usb.ch for enrollment information.
Where is the NCT06353607 trial being conducted?
This trial is being conducted at Basel, Switzerland.
Who is sponsoring the NCT06353607 clinical trial?
NCT06353607 is sponsored by University Hospital, Basel, Switzerland. The principal investigator is Denis Berdajs, Prof. Dr. at University Hospital, Basel, Switzerland. The trial plans to enroll 730 participants.