| NCT ID | NCT07400198 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Jacqueline Montes |
| Condition | Spinal Muscular Atrophy Type 3 |
| Study Type | OBSERVATIONAL |
| Enrollment | 22 participants |
| Start Date | 2026-03-05 |
| Primary Completion | 2027-06-30 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 22 participants in total. It began in 2026-03-05 with a primary completion date of 2027-06-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The objective of this study is to understand how spatiotemporal and kinetic gait parameters are associated with bone health in pwSMA who are receiving DMT. We hypothesize that gait parameters are associated with BMD and can determine fracture risk in pwSMA. This is an observational study that involves one in-clinic visit (approximately 3 hours) with remote follow-up visits (approximately 15 minutes) every 3 months for 1 year to collect fracture and medical history. Each of the assessments included in this study are non-interventional and are not intended as a treatment nor are they at the level of standard of care.
Eligibility Criteria
Inclusion Criteria: * Confirmed diagnosis of 5qSMA * Between 8 and 50 years of age * Able to walk 10 meters without support or an assistive device * All participants who meet the inclusion criteria regardless of treatment status will be included, including those on adjuvant therapies, whether investigational or approved Exclusion Criteria: * Injury or surgery within previous 3 months that would impact ability to perform in-clinic gait assessments * Unwilling or unable to comply with all study procedures * Age less than 8 or over 50 years
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07400198 clinical trial?
This trial is open to participants of all sexes, aged 8 Years or older, up to 50 Years, studying Spinal Muscular Atrophy Type 3. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07400198 currently recruiting?
Yes, NCT07400198 is actively recruiting participants. Contact the research team at chy2112@cumc.columbia.edu for enrollment information.
Where is the NCT07400198 trial being conducted?
This trial is being conducted at New York, United States.
Who is sponsoring the NCT07400198 clinical trial?
NCT07400198 is sponsored by Jacqueline Montes. The trial plans to enroll 22 participants.