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Recruiting NCT04920136

NCT04920136 Gain of Keratinized Mucosa Around Teeth and Dental Implants Using a Combination of Strip Gingival Graft and Acellular Dermal Matrix

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Clinical Trial Summary
NCT ID NCT04920136
Status Recruiting
Phase
Sponsor University of Alabama at Birmingham
Condition Gingival Recession
Study Type INTERVENTIONAL
Enrollment 20 participants
Start Date 2021-09-17
Primary Completion 2026-12-30

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 99 Years
Study Type INTERVENTIONAL
Interventions
Strip Free gingival graft (SGG) + Acellular Dermal Matrix graft (ADM)Free Gingival graft

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 20 participants in total. It began in 2021-09-17 with a primary completion date of 2026-12-30.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This study is to compare the two techniques to achieve change in the tissue quality at areas of lack of Keratinized Tissue (KT) using soft tissue grafting with autogenous graft material (Free Gingival Graft)(FGG) vs Strip gingival graft with acellular dermal matrix (ADM) (SGG+ADM).

Eligibility Criteria

Inclusion Criteria: * English speaking * At least 18 years old * Able to read and understand informed consent document * Patients with teeth/implants lacking keratinized tissue. * Must be a patient of the UAB Dental School * Presence of periodontally healthy, non-carious neighboring teeth, healthy implants or edentulous ridges on either side of the involved site(s) Exclusion Criteria: * Non-English speaking * Less than 18 years old * Smokers/tobacco users (\>10 cigarettes/day) * Patients with systemic pathologies or conditions contraindicating oral surgical procedures or adversely affecting wound healing * Presence of active periodontal disease * Previous soft tissue grafting at the site(s) to be treated

Contact & Investigator

Central Contact

Hussein Basma, DDS, MS

✉ basma86@uab.edu

📞 2059344506

Frequently Asked Questions

Who can join the NCT04920136 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 99 Years, studying Gingival Recession. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT04920136 currently recruiting?

Yes, NCT04920136 is actively recruiting participants. Contact the research team at basma86@uab.edu for enrollment information.

Where is the NCT04920136 trial being conducted?

This trial is being conducted at Birmingham, United States.

Who is sponsoring the NCT04920136 clinical trial?

NCT04920136 is sponsored by University of Alabama at Birmingham. The trial plans to enroll 20 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology