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RecruitingNCT03071536

Furosemide Stress Test Predicting Early Graft Function in Kidney Transplantation

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Trial Parameters

ConditionKidney Function
SponsorKing Chulalongkorn Memorial Hospital
Study TypeINTERVENTIONAL
PhaseN/A
Enrollment180
SexALL
Min Age18 Years
Max Age80 Years
Start Date2016-11-25
Completion2026-05
Interventions
Furosemide Injection

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Brief Summary

Furosemide is an old drug that has been used frequently in the postoperative period of kidney transplantation, aiming to achieve adequate urine output. There is no previous study that directly evaluate the urine response to standardized dose of furosemide in the postoperative period. The objective is to measure the urine output after standardized dose of furosemide is delivered, as a biomarker to predict the graft function in perioperative period.

Eligibility Criteria

Inclusion Criteria: * Deceased donor kidney transplantation at KCMH * informed consent is accepted Exclusion Criteria: * Known allergy to furosemide * Surgical complication of allograft * Urgently needed for dialysis (refractory hypervolemia, uremic symptoms, and hyperkalemia)

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