NCT07677033 Functional Muscle-Bone Incongruity Index (FKUI): A Prospective Observational Study
| NCT ID | NCT07677033 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Kanuni Sultan Suleyman Training and Research Hospital |
| Condition | Osteoporosis |
| Study Type | OBSERVATIONAL |
| Enrollment | 200 participants |
| Start Date | 2026-05-01 |
| Primary Completion | 2027-05-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 200 participants in total. It began in 2026-05-01 with a primary completion date of 2027-05-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The Functional Muscle-Bone Incongruity Index (FKUI) is a novel approach developed to evaluate the relationship between muscle function and bone health. This prospective observational study aims to investigate the clinical applicability of FKUI, which combines handgrip strength, total hip bone mineral density (BMD), and lumbar-hip BMD discordance. Approximately 200 adult participants undergoing routine DXA assessment will be enrolled. The study will examine whether the combined evaluation of muscle function and bone health parameters provides a more comprehensive assessment of musculoskeletal status than individual measures alone.
Eligibility Criteria
Inclusion Criteria: * Age 18 years or older * Attendance at the Physical Medicine and Rehabilitation outpatient clinic * Scheduled to undergo routine bone mineral density assessment by DXA as part of clinical evaluation * Ability to perform handgrip strength testing * Availability of lumbar spine and total hip bone mineral density measurements suitable for analysis * Ability and willingness to provide written informed consent Exclusion Criteria: Exclusion Criteria: * Age younger than 18 years * Secondary causes of osteoporosis (e.g., hyperparathyroidism, Cushing syndrome, malignancy, or other conditions affecting bone metabolism) * History of metabolic bone disease * Major trauma or fracture within the previous 6 months * Upper extremity disorders that may significantly affect handgrip strength measurement (e.g., severe osteoarthritis, neurological disorders, major deformities) * DXA measurements that are technically inadequate or unsuitable for analysis * Refusal or inability to provide written informed consent
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07677033 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Osteoporosis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07677033 currently recruiting?
Yes, NCT07677033 is actively recruiting participants. Contact the research team at dilekunoguzhan@gmail.com for enrollment information.
Where is the NCT07677033 trial being conducted?
This trial is being conducted at Küçükçekmece, Turkey (Türkiye).
Who is sponsoring the NCT07677033 clinical trial?
NCT07677033 is sponsored by Kanuni Sultan Suleyman Training and Research Hospital. The trial plans to enroll 200 participants.