NCT07489963 Functional Impact at 12 Months Post-op of Posterior Cruciate Ligament Conservation During Robotic-assisted Surgery (MAKO) for Total Knee Replacement.
| NCT ID | NCT07489963 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Centre Hospitalier Universitaire de Nīmes |
| Condition | Knee Arthroplasty, Total |
| Study Type | INTERVENTIONAL |
| Enrollment | 300 participants |
| Start Date | 2025-10-10 |
| Primary Completion | 2027-04-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 300 participants in total. It began in 2025-10-10 with a primary completion date of 2027-04-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Studies have been made on the best way to do knee surgery and whether to conserve the posterior cruciate ligament or not during total knee prosthesis insertion is still under debate. However, most of these studies were made before the introduction of robotic knee surgery. It seems timely to do a study comparing these two surgical techniques: preservation versus removal of the posterior cruciate ligament in knee arthroplasty
Eligibility Criteria
Inclusion Criteria: * Patient scheduled for first-intention robotic-assisted total knee replacement (MAKO). * Unilateral replacement, regardless of laterality. * Patient able to answer questionnaires. * Patient willing to undergo usual 12-month follow-up. * Patient has given free and informed consent and has signed the consent form. * Patient affiliated with or benefiting from a health insurance scheme. Exclusion Criteria: * Patient with intraoperative technical impossibility of retaining PCL (flessum \> 20°, flexion stiffening \< 100°). * Previous posterior cruciate ligament surgery. * Post-traumatic gonarthrosis. * Valgus \> 185°. * Patient with septic complication. * Patient participating in another interventional trial. * Patient in an exclusion period determined by another study. * Patient under court protection, guardianship or curatorship. * Patient unable to give consent. * Patients for whom it is impossible to provide informed information. * Pregnant women
Contact & Investigator
Pascal KOUYOUMDJIAN, Pr.
PRINCIPAL INVESTIGATOR
Nîmes University Hospital
Frequently Asked Questions
Who can join the NCT07489963 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Knee Arthroplasty, Total. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07489963 currently recruiting?
Yes, NCT07489963 is actively recruiting participants. Contact the research team at remy.coulomb@chu-nimes.fr for enrollment information.
Where is the NCT07489963 trial being conducted?
This trial is being conducted at Bordeaux, France, Lyon, France, Nîmes, France.
Who is sponsoring the NCT07489963 clinical trial?
NCT07489963 is sponsored by Centre Hospitalier Universitaire de Nīmes. The principal investigator is Pascal KOUYOUMDJIAN, Pr. at Nîmes University Hospital. The trial plans to enroll 300 participants.