NCT07877090 Frontal EEG Dynamics During Anesthesia in Patients With Obesity and Normal Weight
| NCT ID | NCT07877090 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Duzce University |
| Condition | Obesity (BMI>30) |
| Study Type | OBSERVATIONAL |
| Enrollment | 60 participants |
| Start Date | 2026-10-21 |
| Primary Completion | 2027-01-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 60 participants in total. It began in 2026-10-21 with a primary completion date of 2027-01-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This prospective observational study aims to compare frontal electroencephalographic (EEG) spectral dynamics between patients with obesity and normal weight undergoing general anesthesia. The primary objective is to evaluate whether changes in frontal alpha power around propofol-induced loss of consciousness differ between the two BMI groups. Secondary objectives include comparing changes in delta power, the alpha/delta power ratio, and frontal alpha asymmetry around loss of consciousness, as well as evaluating EEG spectral dynamics throughout the intraoperative period. Anesthetic management will be determined by the attending anesthesiologist according to routine clinical practice, without intervention by the study investigators.
Eligibility Criteria
Inclusion Criteria: * Adults aged 18-65 years * Scheduled for elective surgery under general anesthesia * American Society of Anesthesiologists (ASA) physical status I-III * General anesthesia induction performed with propofol * Availability of continuous frontal EEG monitoring (SedLine) during anesthesia * BMI 18.5-24.9 kg/m² for the normal-weight group or BMI ≥30 kg/m² for the obesity group * Ability to provide written informed consent Exclusion Criteria: * \- BMI 25.0-29.9 kg/m² * History of epilepsy or seizure disorder * Known major neurological disease that may affect EEG activity * Altered level of consciousness before anesthesia * Regular use of antiepileptic medications or other drugs known to substantially affect EEG activity * Emergency surgery * Pregnancy * Skin lesions, infection, or other conditions of the forehead preventing appropriate placement of the EEG sensor * Inability to obtain an adequate-quality EEG recording because of technical failure or excessive artifacts * Requirement for substantial deviation from the planned routine anesthetic management that prevents standardized EEG assessment * Refusal to participate or inability to provide written informed consent
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07877090 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Obesity (BMI>30). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07877090 currently recruiting?
Yes, NCT07877090 is actively recruiting participants. Contact the research team at gizem123demir@hotmail.com for enrollment information.
Where is the NCT07877090 trial being conducted?
This trial is being conducted at Düzce, Turkey (Türkiye).
Who is sponsoring the NCT07877090 clinical trial?
NCT07877090 is sponsored by Duzce University. The trial plans to enroll 60 participants.
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