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Recruiting NCT06000761
Frequent Standardized Oral Care Using Human Milk in the Neonatal Intensive Care Unit
Trial Parameters
Condition Ventilator Associated Pneumonia
Sponsor University of Florida
Study Type INTERVENTIONAL
Phase N/A
Enrollment 218
Sex ALL
Min Age 1 Hour
Max Age 3 Days
Start Date 2023-11-23
Completion 2026-09-23
Interventions
Standardized oral Care
Brief Summary
Premature infants are susceptible to complications related to infrequent and non-standardized oral care. Although the benefits of frequent standardized oral care are known to reduce oral dysbiosis (increased level of potentially pathogenic bacteria) and its associated complications in critically ill adults leading to established evidence-based guidelines, no such information exists for VLBW infants. The proposed study will prospectively follow 168 VLBW infants for 4 weeks following birth.
Eligibility Criteria
Inclusion: * Mother ≥18 years of age * ≤ 30 weeks gestation * Born weighing ≤ 1500 grams Exclusion: * Congenital anomalies of the face, lungs, or gastrointestinal system * Not expected to live \> 7 days following delivery.
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