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Recruiting NCT03680677

NCT03680677 Frailty Phenotype Assessments to Optimize Treatment Strategies for Older Patients With Hematologic Malignancies

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Clinical Trial Summary
NCT ID NCT03680677
Status Recruiting
Phase
Sponsor Abramson Cancer Center at Penn Medicine
Condition Leukemia, Acute
Study Type OBSERVATIONAL
Enrollment 20 participants
Start Date 2018-09-21
Primary Completion 2026-06-22

Eligibility & Interventions

Sex All sexes
Min Age 60 Years
Max Age N/A
Study Type OBSERVATIONAL
Interventions
Bone Marrow or Peripheral Blood Graft (BMT)Cancer-directed Therapy or Best Supportive CareFrailty Assessment

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 20 participants in total. It began in 2018-09-21 with a primary completion date of 2026-06-22.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The purpose of this research study is to determine if frailty assessments can be used to predict how well patients aged 60 years and older will do after chemotherapy, CAR T-cell therapy, or allogeneic stem cell transplant.

Eligibility Criteria

Eligibility Criteria Arm A: * Age 60 years or older. * New diagnosis of Acute Leukemia or MDS, or suspected diagnosis. * Able to consent to the study. Eligibility Criteria Arm B: * Age 60 years or older with a hematologic malignancy. * Plan to undergo an allogeneic blood or marrow transplantation or CAR T-cell therapy. * Able to consent to the study.

Contact & Investigator

Central Contact

Shannon McCurdy, MD

✉ penncancertrials@emergingmed.com

📞 855-216-0098

Principal Investigator

Shannon McCurdy, MD

PRINCIPAL INVESTIGATOR

Abramson Cancer Center

Frequently Asked Questions

Who can join the NCT03680677 clinical trial?

This trial is open to participants of all sexes, aged 60 Years or older, studying Leukemia, Acute. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT03680677 currently recruiting?

Yes, NCT03680677 is actively recruiting participants. Contact the research team at penncancertrials@emergingmed.com for enrollment information.

Where is the NCT03680677 trial being conducted?

This trial is being conducted at Philadelphia, United States.

Who is sponsoring the NCT03680677 clinical trial?

NCT03680677 is sponsored by Abramson Cancer Center at Penn Medicine. The principal investigator is Shannon McCurdy, MD at Abramson Cancer Center. The trial plans to enroll 20 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology