NCT06839274 Follicular Volume at the Time of Final Oocyte Maturation in Poor Responders, and Its Correlation With Oocyte Maturity
| NCT ID | NCT06839274 |
| Status | Recruiting |
| Phase | — |
| Sponsor | ART Fertility Clinics LLC |
| Condition | OVARIAN STIMULATION |
| Study Type | OBSERVATIONAL |
| Enrollment | 100 participants |
| Start Date | 2025-03-27 |
| Primary Completion | 2026-12-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 100 participants in total. It began in 2025-03-27 with a primary completion date of 2026-12-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Women with a severely diminished ovarian reserve and monofollicular growth are at a higher risk of premature ovulation as well as poor quality oocytes. Our group showed previously that women with severely diminished ovarian reserve benefit from receiving the final oocyte maturation at smaller follicle sizes in terms of reducing the risk of premature ovulation and finding mature oocytes even out of small size follicles. Adding the measurement of the follicular volume at the time of final oocyte maturation might provide more information on the proper timing of trigger administration compared to the follicular size alone, hormonal profile as well as previous stimulation attempts. Setting a cutoff value of follicular volume for trigger might help to avoid premature ovulation and possibly increase the chances of ending up with a euploid embryo.
Eligibility Criteria
Inclusion Criteria: * Reproductive age group: 18 -48 * undergoing ovarian stimulation for oocyte vetrification * undergoing IVF/ ICSI with PGT-A / PGT-M / PGT- Sr * less than or equal to 3 AFC on initiation of stimulation * follicular phase stimulation Exclusion Criteria: * surgically retrieved sperm
Contact & Investigator
Barbara Lawrenz, PhD
STUDY DIRECTOR
ART Fertility Clinics LLC
Frequently Asked Questions
Who can join the NCT06839274 clinical trial?
This trial is open to female participants only, aged 18 Years or older, up to 48 Years, studying OVARIAN STIMULATION. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06839274 currently recruiting?
Yes, NCT06839274 is actively recruiting participants. Contact the research team at jonalyn.edades@artfertilityclinics.com for enrollment information.
Where is the NCT06839274 trial being conducted?
This trial is being conducted at Abu Dhabi, United Arab Emirates.
Who is sponsoring the NCT06839274 clinical trial?
NCT06839274 is sponsored by ART Fertility Clinics LLC. The principal investigator is Barbara Lawrenz, PhD at ART Fertility Clinics LLC. The trial plans to enroll 100 participants.