NCT07214246 Follicular Fluid microRNAs in Ovarian Aging and Reproduction
| NCT ID | NCT07214246 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Central Florida |
| Condition | Ovarian Aging |
| Study Type | OBSERVATIONAL |
| Enrollment | 100 participants |
| Start Date | 2025-09-22 |
| Primary Completion | 2026-09 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 100 participants in total. It began in 2025-09-22 with a primary completion date of 2026-09.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of this study is to investigate the role of exosomal microRNAs (miRNAs) in follicular fluid (FF) as biomarkers of ovarian aging and predictors of in vitro fertilization (IVF) outcomes. The goal is to identify noninvasive molecular markers that correlate with oocyte quality and reproductive potential, particularly in women of advanced maternal age.
Eligibility Criteria
Inclusion Criteria: * Women undergoing IVF treatment due to male factor infertility or nonovarian causes. * Age groups: younger women \<31 years and older women \>38 years. * Regular menstrual cycles. * Willing and able to provide informed consent. Exclusion Criteria: * Minors (under 18 years) and women aged 32-37 years * Diagnosis of polycystic ovarian syndrome (PCOS). * History of recurrent pregnancy loss. * Presence of endometriosis. * Diagnosis of ovarian insufficiency. * Metabolic disorders (e.g., diabetes). * History of ovarian surgery or chemotherapy. * Any condition that might impact follicular fluid quality or IVF outcomes.
Contact & Investigator
Michal Masternak, PhD
PRINCIPAL INVESTIGATOR
University of Central Florida
Frequently Asked Questions
Who can join the NCT07214246 clinical trial?
This trial is open to female participants only, aged 18 Years or older, studying Ovarian Aging. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07214246 currently recruiting?
Yes, NCT07214246 is actively recruiting participants. Contact the research team at Amoy.Fraser@ucf.edu for enrollment information.
Where is the NCT07214246 trial being conducted?
This trial is being conducted at Orlando, United States.
Who is sponsoring the NCT07214246 clinical trial?
NCT07214246 is sponsored by University of Central Florida. The principal investigator is Michal Masternak, PhD at University of Central Florida. The trial plans to enroll 100 participants.