NCT06779578 Fluoroscopic-Guided Bipolar Versus Monopolar Pulsed Radiofrequency for Refractory Trigeminal Neuralgia
| NCT ID | NCT06779578 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Alexandria University |
| Condition | Trigeminal Neuralgia |
| Study Type | INTERVENTIONAL |
| Enrollment | 20 participants |
| Start Date | 2024-01-01 |
| Primary Completion | 2025-06-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 20 participants in total. It began in 2024-01-01 with a primary completion date of 2025-06-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
A prospective exploratory study aiming at comparing pulsed bipolar versus pulsed unipolar radiofrequency ablation in patients with medically refractory trigeminal neuralgia.
Eligibility Criteria
Inclusion Criteria: 1. Patients with a definitive diagnosis of classical TN based on the third version of the International Classification of Headache Disorders (ICHD-3). 2. Either purely paroxysmal classical TN or classical TN with concomitant chronic pain. 3. Patients with idiopathic TN, with symptomatic clinical topography of V2 and/or V3. 4. Patients with brain magnetic resonance imaging (MRI) unremarkable for structural etiology for the trigeminal pain. 5. Patients with medically refractory TN defined as pain persisting beyond three months at a level of ≥5/10 after monotherapy or polytherapy in appropriate medical doses. Exclusion Criteria: 1. Painful trigeminal neuropathy based on the third version of the International Classification of Headache Disorders (ICHD-3). 2. Trigeminal neuralgia with V1 symptomatic clinical topography. 3. Trigeminal neuralgia comorbid with other atypical facial pain disorders. 4. Structural TN e.g., due to vascular compression, posterior fossa tumors, central demyelination, …etc. 5. Patients exposed to previous radiofrequency procedures, as this may impair the nerve response to current PRF. 6. Patients who refused to participate in the study.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06779578 clinical trial?
This trial is open to participants of all sexes, studying Trigeminal Neuralgia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06779578 currently recruiting?
Yes, NCT06779578 is actively recruiting participants. Contact the research team at eman.ameen@alexmed.edu.eg for enrollment information.
Where is the NCT06779578 trial being conducted?
This trial is being conducted at Alexandria, Egypt, Cairo, Egypt.
Who is sponsoring the NCT06779578 clinical trial?
NCT06779578 is sponsored by Alexandria University. The trial plans to enroll 20 participants.