NCT05025774 Fitness and Lung Function Among Survivors of Heart Transplant, Leukemia and Infant BPD Through Exercise
| NCT ID | NCT05025774 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Masonic Cancer Center, University of Minnesota |
| Condition | Chronic Lung Disease |
| Study Type | OBSERVATIONAL |
| Enrollment | 90 participants |
| Start Date | 2025-03-14 |
| Primary Completion | 2026-11-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 90 participants in total. It began in 2025-03-14 with a primary completion date of 2026-11-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study aims to more accurately assess cardiac function, ventilation and exercise capacity in a non-invasive fashion, and to better characterize exercise intolerance in the setting of three populations of individuals with chronic diseases of childhood (acute lymphoblastic leukemia (ALL), chronic lung disease (CLD) of prematurity, and post-heart transplant (HT))
Eligibility Criteria
Inclusion Criteria: * Cases: * Acute lymphoblastic leukemia survivor, OR living with chronic lung disease of prematurity, OR living with heart transplant * 8-25 years old * Height: ≥ 48 inches * Ambulatory without assistance * English speaking * Normotensive (\<95th percentile for age; okay if managed with antihypertensive medication) * SpO2 \>92% * Not pregnant * ALL survivor specific: must have completed therapy ≥ 3 months prior to study entry * Controls * 8-25 years old * Height: ≥ 48 inches * Ambulatory without assistance * English speaking * No history of arrhythmia or known cardiac dysfunction at baseline * Normotensive (\<95th percentile for age; okay if managed with antihypertensive medication) * SpO2 \>95% * Not pregnant Exclusion Criteria: * Cases: * ALL specific: received cranial radiation, bone marrow transplant recipients * Investigator or patient's primary physician deems the patient unsuitable for the study * Controls: * History of malignancy, CLD or HT or any other diagnosis which may reduce cardiorespiratory function * Investigator deems the patient unsuitable for the study
Contact & Investigator
Pianosi Paolo, MD
PRINCIPAL INVESTIGATOR
Masonic Children's Hospital, University of Minnesota
Frequently Asked Questions
Who can join the NCT05025774 clinical trial?
This trial is open to participants of all sexes, aged 8 Years or older, up to 25 Years, studying Chronic Lung Disease. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05025774 currently recruiting?
Yes, NCT05025774 is actively recruiting participants. Contact the research team at bake0257@umn.edu for enrollment information.
Where is the NCT05025774 trial being conducted?
This trial is being conducted at Minneapolis, United States.
Who is sponsoring the NCT05025774 clinical trial?
NCT05025774 is sponsored by Masonic Cancer Center, University of Minnesota. The principal investigator is Pianosi Paolo, MD at Masonic Children's Hospital, University of Minnesota. The trial plans to enroll 90 participants.