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Recruiting NCT06381245

First-time Ablation of Atrial Fibrillation Registry

Trial Parameters

Condition Atrial Fibrillation
Sponsor Medical University of Warsaw
Study Type OBSERVATIONAL
Phase N/A
Enrollment 400
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2023-12-01
Completion 2026-03-31
Interventions
PPG-based remote heart rhythm/rate monitoringECG-based remote heart rhythm/rate monitoringTransthoracic and transesophageal echocardiography examination

Brief Summary

Atrial fibrillation (AF) is a prevalent cardiac arrhythmia affecting millions globally, with projections indicating a doubling of cases by 2050. AF is linked to heightened cardiovascular risks like stroke and increased healthcare costs. Ablation, targeting the arrhythmia substrate, is a method to manage AF, yet recurrence rates remain high (20-45% in the first year). Studies highlight the impact of comorbidities, AF characteristics, ablation techniques, and myocardial remodeling markers on AF progression and ablation efficacy. However, there's no definitive guidance on selecting these factors for predicting treatment success. The aim of this study is to investigate predictors of successful AF ablation in the following areas: (a) clinical factors, (b) electrophysiological, (c) electrocardiographic, (d) ultrasound, (e) cardiac anatomy, (f) biomarkers.

Eligibility Criteria

Inclusion Criteria: * paroxysmal or persistent AF * first-time ablation of AF Exclusion Criteria: * patients unable to give informed consent * serious health condition existing before ablation

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