Fertility-sparing Therapy for Patients With Stage IA Endometrial Cancer
Trial Parameters
Brief Summary
The goal of this clinical trial is to explore the feasibility and outcome of fertility-sparing therapy in Stage IA G1-G2 Endometrial Cancer with less than 1/2 myometrial invasion. Researchers will render participants indication-extended fertility-sparing therapy. Researchers will compare the myometrial invasion group with the no myometrial invasion group to see if it is possible to propose an extension indication of fertility-sparing therapy for endometrial cancer.
Eligibility Criteria
Inclusion Criteria: * Stage IA (FIGO 2009) ; * Pathological diagnosis: endometrial adenocarcinoma G1-G2; * MRI or ultrasound: tumor limited to endometrium or invading less than 1/2 of myometrium； * 18 years old ≤ Age ≤ 45 years old; * With a strong desire for fertility preservation； * Sign the informed consent. Exclusion Criteria: * Complicated with any other malignancy； * Contraindications to conservative treatment； * Contraindications to progestin use; * Contraindications to pregnancy, or judged by the researcher to be unfit for pregnancy or delivery.