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Recruiting NCT04637438

NCT04637438 Fecal Microbiota Transplantation in Postoperative Crohn's Disease

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Clinical Trial Summary
NCT ID NCT04637438
Status Recruiting
Phase
Sponsor Tampere University Hospital
Condition Crohn Disease
Study Type INTERVENTIONAL
Enrollment 20 participants
Start Date 2021-05-18
Primary Completion 2023-12

Trial Parameters

Condition Crohn Disease
Sponsor Tampere University Hospital
Study Type INTERVENTIONAL
Phase N/A
Enrollment 20
Sex ALL
Min Age 18 Years
Max Age 120 Years
Start Date 2021-05-18
Completion 2023-12
Interventions
Fecal Microbiota TransplantationPlacebo

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Brief Summary

This pilot study aims to detect possible trends or signals suggesting efficacy of FMT on prevention of delay of POR, to determine the safety of FMT in post operative CD, and asses if a full randomised controlled trial is feasible in this setting. With microbiota analysis we aim to assess if changes in gut microbiota are related to disease course of CD after operation.

Eligibility Criteria

Inclusion Criteria: * Over 18 years * Able to provide written consent * Stricturing and/or fistulizing Crohn's disease needing ileocecal or ileal resection Exclusion Criteria: * Pregnancy * Active infection, abscess or fistula at the time of the first colonoscopy * Life expectancy \<1 year * Unable to provide written consent * Use on antibiotics or probiotics at the time of first colonoscopy

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