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Recruiting NCT06871267

NCT06871267 Dietary Modification In Inflammatory Bowel Disease Patients

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Clinical Trial Summary
NCT ID NCT06871267
Status Recruiting
Phase
Sponsor University of Malaya
Condition Crohn Disease
Study Type INTERVENTIONAL
Enrollment 74 participants
Start Date 2025-03-01
Primary Completion 2025-09-10

Trial Parameters

Condition Crohn Disease
Sponsor University of Malaya
Study Type INTERVENTIONAL
Phase N/A
Enrollment 74
Sex ALL
Min Age 18 Years
Max Age 50 Years
Start Date 2025-03-01
Completion 2025-09-10
Interventions
General Healthy DietCrohn's Disease Exclusion Diet (CDED)

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Brief Summary

This research project aimed to develop a culturally appropriate Asian Inflammatory Bowel Disease Diet for the Malaysian population, based on the Crohn's disease exclusion diet (CDED). The study will be conducted in inflammatory bowel disease patients in University Malaya Medical Centre, which are ulcerative colitis and Crohn's disease patients. The objectives of this study are to assess the impact of diet in clinical outcome and gut microbiota changes in patients with inflammatory bowel disease (IBD). The study duration spans 24 weeks, during which comprehensive follow-ups will be conducted at 0, 6, 12, and 24 weeks, respectively. At each follow-up session, participants will be requested to provide stool and blood samples for meticulous assessment of clinical and biochemical responses.

Eligibility Criteria

Inclusion Criteria: * Confirmed diagnosis of Crohn's disease according to established clinical, endoscopic, and histological criteria. * Mild to moderate diseases (150 to 220 points). * Written informed consent obtained. Exclusion Criteria: * Presence of stoma. * Surgery within 6 months prior to randomization. * Patient on exclusive enteral nutrition (EEN).

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