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Recruiting NCT03516461

Fecal Microbiota Transplantation for Radiation Enteritis

Trial Parameters

Condition Radiation Enteritis
Sponsor The Second Hospital of Nanjing Medical University
Study Type INTERVENTIONAL
Phase N/A
Enrollment 70
Sex ALL
Min Age 18 Years
Max Age 85 Years
Start Date 2018-01-07
Completion 2025-07-01
Interventions
Fecal Microbiota Transplantation (FMT)

Brief Summary

Radiation enteritis is one of the most feared complications after abdominal or pelvic radiation therapy.The gut microbiota is considered to constitute a "microbial organ" which has pivotal roles in the intestinal diseases and body metabolism. Evidence from animal studies demonstrated the link between intestinal bacteria and radiation enteritis. This clinical trial aims to evaluate the efficacy and safety of fecal microbiota transplantation (FMT) for radiation enteritis.

Eligibility Criteria

Inclusion Criteria: 1. age ≥18 years old; 2. Radiation enteritis diagnosed by colonoscopy after finishing radiotherapy. Exclusion Criteria: 1. Patients who were pregnant or nursing; 2. Patients who were unable or unwilling to undergo a gastroscopy; 3. Patients who had gastrointestinal infection; 4. Patients with cardiopulmonary failure.

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