NCT07344623 Factors Associated With Clinical Pregnancy Outcomes in Intrauterine Insemination (IUI) Cycles
| NCT ID | NCT07344623 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Chinese University of Hong Kong |
| Condition | Reproductive Issues |
| Study Type | OBSERVATIONAL |
| Enrollment | 3,000 participants |
| Start Date | 2026-01-13 |
| Primary Completion | 2027-07-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 3,000 participants in total. It began in 2026-01-13 with a primary completion date of 2027-07-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Hypotheses: We hypothesize that variations in hormonal profiles (LH, estradiol, progesterone) during ovarian stimulation, follicular response, endometrial characteristics, and sperm quality parameters are significantly associated with clinical pregnancy outcomes in intrauterine insemination (IUI) cycles. Aims * To investigate the association between hormonal profiles on the trigger day (LH, estradiol, progesterone), follicular response, endometrial thickness, and sperm parameters with clinical pregnancy outcomes in IUI cycles. * To develop and validate a predictive model for clinical pregnancy incorporating key determinants such as female age, hormonal response, endometrial characteristics, and sperm quality. * To compare natural and gonadotropin-stimulated IUI cycles in terms of hormonal profiles, pregnancy outcomes, and cost-effectiveness. Primary Outcome Clinical pregnancy rate (CPR), defined as the presence of a gestational sac with a fetal heartbeat on ultrasound at approximately 6 weeks of gestation following intrauterine insemination. Secondary Outcomes * Biochemical pregnancy rate. * Ongoing pregnancy rate * Live birth rate
Eligibility Criteria
Inclusion Criteria: * Couples who underwent at least one IUI-intrauterine insemination cycle. Exclusion Criteria: * Couples who used donor sperm. * Cases with missing core outcome data
Frequently Asked Questions
Who can join the NCT07344623 clinical trial?
This trial is open to female participants only, aged 18 Years or older, up to 42 Years, studying Reproductive Issues. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07344623 currently recruiting?
Yes, NCT07344623 is actively recruiting participants. Visit ClinicalTrials.gov or contact Chinese University of Hong Kong to inquire about joining.
Where is the NCT07344623 trial being conducted?
This trial is being conducted at Hong Kong, China.
Who is sponsoring the NCT07344623 clinical trial?
NCT07344623 is sponsored by Chinese University of Hong Kong. The trial plans to enroll 3,000 participants.