External Oblique Intercostal Block Versus Transversus Abdominis Plane Combined With Rectus Sheath Block on Postoperative Pain in Laparoscopic Radical Gastrectomy
Trial Parameters
Brief Summary
Postoperative pain is highly prevalent following laparoscopic radical gastrectomy. Although Transversus abdominis plane block combined with rectus sheath block(TAP+RSB） can effectively alleviate this pain, it still has many limitations. The external oblique intercostal plane block (EOIB) is a novel nerve block technique that may provide well postoperative analgesia for upper abdominal surgery. Therefore, this study employs a non-inferiority randomized controlled trial design to verify that the analgesic effect of EOIB is not inferior to that of ESPB, thereby offering more options for regional analgesia strategies in laparoscopic radical gastrectomy.
Eligibility Criteria
Inclusion Criteria: * Patients aged over 18 years * Classified as ASA I-III * Scheduled for elective laparoscopic radical gastrectomy under general anesthesia * Voluntarily participated and provided written informed consent. Exclusion Criteria: * Chronic opioid dependence or prior use of analgesic medications for \>3 months; * Inability to communicate due to severe dementia, language barriers, or terminal illness; * History of central and/or peripheral nervous system disorders; * Severe renal insufficiency (serum creatinine \>442 μmol/L or requiring renal replacement therapy) or severe hepatic insufficiency (Child-Pugh class C); * Allergy to local anesthetics. * Expected to be transferred to ICU after surgery. * Refuse patient control agenesia after surgery.