Expression of Genes Relating Hypertension and Efficacy of 4-7-8 Breathing Control on Reducing Blood Pressure
Trial Parameters
Brief Summary
This study consists of two sub-studies. Study 1 investigates gene expression related to the development of hypertension in Thailand, and Study 2 examines the effectiveness of the 4-7-8 breathing technique in reducing blood pressure in individuals with hypertension.
Eligibility Criteria
Study 1: 1. Group of individuals with hypertension Inclusion Criteria: * Male or female * Aged between 18-59 years * Of Thai ethnicity * Diagnosed with hypertension, defined as having an SBP of 140 mmHg or higher, or a DBP of 90 mmHg or higher, or having previously been diagnosed with hypertension and currently taking antihypertensive medication * Originally from various regions of Thailand and currently residing in the eastern region Exclusion Criteria: * Has heart disease, such as valvular stenosis or regurgitation, coronary artery disease, or heart failure * Has obesity, defined as having a body mass index (BMI) of 30 kg/m² or higher * Has a fever or is currently experiencing an infectious disease, such as COVID-19, the flu, or other infections 2. Group of individuals with normal blood pressure Inclusion Criteria: * Male or female * Aged between 18-59 years * Of Thai ethnicity * Does not have hypertension, defined as having an SBP below 130 mmHg and a DBP below 85 mmHg, with no prio