NCT07288905 Exploring the Effects of Exercise Combined With BFRT on Healthy and Patients With CKD
| NCT ID | NCT07288905 |
| Status | Recruiting |
| Phase | — |
| Sponsor | National Cheng Kung University |
| Condition | Chronic Kidney Disease |
| Study Type | INTERVENTIONAL |
| Enrollment | 120 participants |
| Start Date | 2025-10-04 |
| Primary Completion | 2027-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 120 participants in total. It began in 2025-10-04 with a primary completion date of 2027-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Investigate the effects of exercise training on the cardiopulmonary function and exercise capacity in healthy and CKD patients
Eligibility Criteria
Healthy Inclusion Criteria: • Aged 20\~85 years old Exclusion Criteria: * Severe uncontrolled metabolic diseases (e.g., hyperthyroidism, diabetes, hypertension, hyperlipidemia, etc.) * Severe pulmonary or cardiovascular diseases (e.g., pulmonary hypertension, chronic obstructive pulmonary disease (COPD), heart failure, cardiac arrhythmia) * Presence of a cardiac pacemaker or a history of myocardial infarction within the past six months * Severe musculoskeletal or neuromuscular disorders (e.g., advanced arthritis, limb amputation, post-polio syndrome, Parkinson's disease) * Unstable vital signs (e.g., systolic blood pressure ≥180 mmHg, diastolic blood pressure ≥90 mmHg, requiring vasopressors, or resting heart rate \>100 bpm) * Prone to bruising * Recent inflection \< 1 month * Pregnancy * Kidney function impairment * Cancer * Simultaneously participating in other research CKD Inclusion criteria: * Aged 20\~85 years old * eGFR\< 90 ml/min/1.73 m2 over 3 months * Stable condition without worsening in the past 3 months * Ability to understand and follow verbal commends and cooperate with an exercise training program Exclusion criteria: * Severe uncontrolled metabolic diseases (e.g., hyperthyroidism, diabetes, hypertension, hyperlipidemia, etc.) * Severe pulmonary or cardiovascular diseases (e.g., pulmonary hypertension, chronic obstructive pulmonary disease (COPD), heart failure, cardiac arrhythmia) * Presence of a cardiac pacemaker or a history of myocardial infarction within the past six months * Severe musculoskeletal or neuromuscular disorders (e.g., advanced arthritis, limb amputation, post-polio syndrome, Parkinson's disease) * Unstable vital signs (e.g., systolic blood pressure ≥180 mmHg, diastolic blood pressure ≥90 mmHg, requiring vasopressors, or resting heart rate \>100 bpm) * Abnormal blood biochemical parameters (e.g., white blood cell count \<2500/mm³, hemoglobin \<8 mg/dL, total bilirubin \>3 mg/dL, liver enzymes (GOT/AST, GPT/ALT) \>3 times the upper limit of normal, platelet count \<75,000/mm³ * Sensory or motor dysfunctions that affect walking ability * Diagnosed systemic diseases under ongoing treatment (e.g., systemic lupus erythematosus, cancer, malignancies).
Contact & Investigator
Kun-Ling Tasi, PhD
PRINCIPAL INVESTIGATOR
Department of Physical Therapy, National Cheng Kung University
Frequently Asked Questions
Who can join the NCT07288905 clinical trial?
This trial is open to participants of all sexes, aged 20 Years or older, up to 85 Years, studying Chronic Kidney Disease. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07288905 currently recruiting?
Yes, NCT07288905 is actively recruiting participants. Contact the research team at Kunlingtsai@mail.ncku.edu.tw for enrollment information.
Where is the NCT07288905 trial being conducted?
This trial is being conducted at Tainan, Taiwan.
Who is sponsoring the NCT07288905 clinical trial?
NCT07288905 is sponsored by National Cheng Kung University. The principal investigator is Kun-Ling Tasi, PhD at Department of Physical Therapy, National Cheng Kung University. The trial plans to enroll 120 participants.
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