NCT07228728 Exploring the Cutaneous Immune Response to Skin Massage in Early Life
| NCT ID | NCT07228728 |
| Status | Recruiting |
| Phase | — |
| Sponsor | King's College London |
| Condition | Skin Massage |
| Study Type | INTERVENTIONAL |
| Enrollment | 109 participants |
| Start Date | 2026-01-02 |
| Primary Completion | 2027-03-30 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 109 participants in total. It began in 2026-01-02 with a primary completion date of 2027-03-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This project aims to study whether regular skin massage in babies induces cutaneous inflammation and whether this inflammatory response is amplified in those receiving daily (vs bi-weekly or no) skin massage over an 8 week period. Specifically, it aims to: 1. Establish if massage increases /decreases immune signals in the skin. 2. Clarify if the effects of massage are enhanced with the frequency of massage. 3.) Assess changes in skin biology as a consequence of skin massage. 4.) Determine if massage impacts skin barrier function in the early years of life.
Eligibility Criteria
Inclusion Criteria: 1. Healthy babies born at term up to 6 months old 2. Ability of parents/guardians/caregivers to provide written informed consent for study participation 3. Willingness of parents/guardians/caregivers to comply with all study requirements. Exclusion Criteria: 1. Parents/guardians/caregivers unable to give informed consent. 2. Personal history of inflammatory skin disease (in particular atopic dermatitis) 3. Active involvement in another interventional research study
Contact & Investigator
Carsten Flohr
PRINCIPAL INVESTIGATOR
Guy's and St Thomas' NHS Foundation Trust
Frequently Asked Questions
Who can join the NCT07228728 clinical trial?
This trial is open to participants of all sexes, aged 0 Months or older, up to 6 Months, studying Skin Massage. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07228728 currently recruiting?
Yes, NCT07228728 is actively recruiting participants. Contact the research team at gstt.cutie.study@nhs.net for enrollment information.
Where is the NCT07228728 trial being conducted?
This trial is being conducted at London, United Kingdom.
Who is sponsoring the NCT07228728 clinical trial?
NCT07228728 is sponsored by King's College London. The principal investigator is Carsten Flohr at Guy's and St Thomas' NHS Foundation Trust. The trial plans to enroll 109 participants.